A murine glaucoma model induced by rapid in vivo photopolymerization of hyaluronic acid glycidyl methacrylate

Glaucoma is an optic neuropathy commonly associated with elevated intraocular pressure (IOP) resulting in progressive loss of retinal ganglion cells (RGCs) and optic nerve degeneration, leading to blindness. New therapeutic approaches that better preserve the visual field by promoting survival and h...

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Veröffentlicht in:	PloS one 2018-06, Vol.13 (6), p.e0196529-e0196529
Hauptverfasser:	Guo, Chenying, Qu, Xin, Rangaswamy, Nalini, Leehy, Barrett, Xiang, Chuanxi, Rice, Dennis, Prasanna, Ganesh
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Animals Astrocytes Axons Biology and Life Sciences Biomedical research Blindness Brain research Chronic Disease Crosslinking Degeneration Disease Models, Animal Epoxy Compounds - adverse effects Epoxy Compounds - chemistry Epoxy Compounds - pharmacology Female Glaucoma Glaucoma - chemically induced Glaucoma - metabolism Glaucoma - pathology Humans Hyaluronic acid Hyaluronic Acid - adverse effects Hyaluronic Acid - chemistry Hyaluronic Acid - pharmacology Hypertension Intraocular pressure Male Medicine and Health Sciences Methacrylates - adverse effects Methacrylates - chemistry Methacrylates - pharmacology Mice Microglia Neuropathy Optic nerve Optic Nerve Diseases - chemically induced Optic Nerve Diseases - metabolism Optic Nerve Diseases - pathology Optic neuropathy Outflow Photochemical Processes Photopolymerization Retina Retinal ganglion cells Retinal Ganglion Cells - metabolism Retinal Ganglion Cells - pathology Stability Ultraviolet radiation Ultraviolet Rays Visual field Visual fields
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