Mycosis fungoides progression could be regulated by microRNAs

Differentiating early mycosis fungoides (MF) from inflammatory dermatitis is a challenge. We compare the differential expression profile of early-stage MF samples and benign inflammatory dermatoses using microRNA (miRNA) arrays. 114 miRNAs were found to be dysregulated between these entities. The se...

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Veröffentlicht in:	PloS one 2018-06, Vol.13 (6), p.e0198477-e0198477
Hauptverfasser:	Manso, Rebeca, Martínez-Magunacelaya, Nerea, Eraña-Tomás, Itziar, Monsalvez, Verónica, Rodríguez-Peralto, José L, Ortiz-Romero, Pablo-L, Santonja, Carlos, Cristóbal, Ion, Piris, Miguel A, Rodríguez-Pinilla, Socorro M
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Analysis Apoptosis Biology and life sciences Biomarkers, Tumor - genetics Cancer Cell cycle Cell Line, Tumor Deregulation Dermatitis Dermatology Development and progression Disease Progression Female Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Foxp3 protein Fungal infections Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Humans Immunohistochemistry Inflammation Lesions Lymphoma Male Medicine and Health Sciences MicroRNA MicroRNAs MicroRNAs - genetics miRNA Mycosis Mycosis fungoides Mycosis Fungoides - genetics Mycosis Fungoides - metabolism Paraffin Pathogenesis Pathology Polymerase chain reaction Research and Analysis Methods Ribonucleic acid RNA Skin Neoplasms - genetics Skin Neoplasms - metabolism
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