Nestin in the epididymis is expressed in vascular wall cells and is regulated during postnatal development and in case of testosterone deficiency

Vascular smooth muscle cells (SMCs), distinguished by the expression of the neuronal stem cell marker nestin, may represent stem cell-like progenitor cells in various organs including the testis. We investigated epididymal tissues of adult nestin-GFP mice, rats after Leydig cell depletion via ethane...

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Veröffentlicht in:	PloS one 2018-06, Vol.13 (6), p.e0194585-e0194585
Hauptverfasser:	Reckmann, Ansgar N, Tomczyk, Claudia U M, Davidoff, Michail S, Michurina, Tatyana V, Arnhold, Stefan, Müller, Dieter, Mietens, Andrea, Middendorff, Ralf
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Androgen receptors Androgens Animals Biology Biology and Life Sciences Cells (biology) Endothelial cells Epididymis Epididymis - blood supply Epididymis - growth & development Epididymis - pathology Ethane Gene Expression Regulation Genetic aspects Human tissues Laboratories Localization Male Medicine and Health Sciences Mice Mice, Transgenic Muscle, Smooth, Vascular - metabolism Muscle, Smooth, Vascular - pathology Muscles Myocytes, Smooth Muscle - metabolism Myocytes, Smooth Muscle - pathology Myogenesis Nervous system Nestin Nestin - biosynthesis Neural stem cells Organs Physiological aspects Progenitor cells Proliferating cell nuclear antigen Proteins Rats Research and Analysis Methods Rodents Smooth muscle Stem cell transplantation Stem cells Testosterone Testosterone - deficiency Tissues
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