Low-molecular-weight heparin venous thromboprophylaxis in critically ill patients with renal dysfunction: A subgroup analysis of the PROTECT trial

There is concern about excessive bleeding when low-molecular-weight heparins (LMWHs) are used for venous thromboembolism (VTE) prophylaxis in renal dysfunction. Our objective was to evaluate whether LMWH VTE prophylaxis was safe and effective in critically ill patients with renal dysfunction by cond...

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Veröffentlicht in:	PloS one 2018-06, Vol.13 (6), p.e0198285-e0198285
Hauptverfasser:	Pai, Menaka, Adhikari, Neill K J, Ostermann, Marlies, Heels-Ansdell, Diane, Douketis, James D, Skrobik, Yoanna, Qushmaq, Ismael, Meade, Maureen, Guyatt, Gordon, Geerts, William, Walsh, Michael W, Crowther, Mark A, Friedrich, Jan O, Burry, Lisa, Bellomo, Rinaldo, Brandão da Silva, Nilton, Costa Filho, Rubens, Cox, Michael J, Alves Silva, Suzana, Cook, Deborah J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Anticoagulants Anticoagulants - therapeutic use Bioaccumulation Bleeding Care and treatment Chemoprevention - methods Creatinine Critical care Critical Care - methods Critical Illness - therapy Dialysis Dosage and administration Drug dosages Drug therapy Embolism Embolisms End-stage renal disease Female Glycoproteins Health aspects Heparin Heparin, Low-Molecular-Weight - therapeutic use Hospitals Humans Intensive care Internal medicine Kidney diseases Kidney failure Kidney Failure, Chronic - drug therapy Laboratories Male Medical research Medicine Medicine and Health Sciences Methods Middle Aged Molecular chains Patients Peritoneal dialysis Prophylaxis Regression analysis Renal function Research and Analysis Methods Research methodology Sick persons Studies Subgroups Thromboembolism Thrombosis Venous Thromboembolism - prevention & control Venous thrombosis
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