Choice of time horizon critical in estimating costs and effects of changes to HIV programmes

Uganda changed its antiretroviral therapy guidelines in 2014, increasing the CD4 threshold for antiretroviral therapy initiation from 350 cells/μl to 500 cells/μl. We investigate what effect this change in policy is likely to have on HIV incidence, morbidity, and programme costs, and estimate the co...

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Veröffentlicht in:	PloS one 2018-05, Vol.13 (5), p.e0196480
Hauptverfasser:	McCreesh, Nicky, Andrianakis, Ioannis, Nsubuga, Rebecca N, Strong, Mark, Vernon, Ian, McKinley, Trevelyan J, Oakley, Jeremy E, Goldstein, Michael, Hayes, Richard, White, Richard G
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Analysis Anti-HIV Agents - economics Anti-HIV Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Biology and Life Sciences Calibration CD4 antigen CD4 Lymphocyte Count Cost analysis Cost-Benefit Analysis Demographics Disease transmission Drug therapy Economic aspects Epidemiology Female Funding Health Policy - economics HIV HIV Infections - drug therapy HIV Infections - economics HIV Infections - epidemiology Human immunodeficiency virus Humans Hygiene Incidence Male Mathematical models Medical tests Medicine Medicine and Health Sciences Model matching Models, Economic Morbidity Mortality Parameters People and Places Population Quality-Adjusted Life Years Research and Analysis Methods Sexual behavior Sexually transmitted diseases Social Sciences Software STD Studies Therapy Time Factors Uganda - epidemiology Uncertainty
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