Oxidative stress enhances neurodegeneration markers induced by herpes simplex virus type 1 infection in human neuroblastoma cells

Mounting evidence suggests that Herpes simplex virus type 1 (HSV-1) is involved in the pathogenesis of Alzheimer's disease (AD). Previous work from our laboratory has shown HSV-1 infection to induce the most important pathological hallmarks of AD brains. Oxidative damage is one of the earliest...

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Veröffentlicht in:	PloS one 2013-10, Vol.8 (10), p.e75842-e75842
Hauptverfasser:	Santana, Soraya, Sastre, Isabel, Recuero, Maria, Bullido, Maria J, Aldudo, Jesus
Format:	Artikel
Sprache:	eng
Schlagworte:	Accumulation Advertising executives Alzheimer Disease - metabolism Alzheimer Disease - virology Alzheimer's disease Autophagy Biomarkers Brain damage Cell death Cell Line, Tumor Disease Fluorescent Antibody Technique Free radicals Health aspects Herpes simplex Herpes simplex virus Herpes viruses Herpesviridae Infections - complications Herpesviridae Infections - metabolism Herpesvirus 1, Human - pathogenicity Humans Hydrogen peroxide Immunoglobulins Infection Infections Kinases Lipid peroxidation Medical research Metabolism Neuroblastoma Neuroblastoma - metabolism Neuroblastoma cells Neurodegeneration Oxidative stress Oxidative Stress - physiology Pathogenesis Phagocytosis Proteins Secretion Viruses
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