Predictive saccades in children and adults: A combined fMRI and eye tracking study
Saccades were assessed in 21 adults (age 24 years, SD = 4) and 15 children (age 11 years, SD = 1), using combined functional magnetic resonance imaging (fMRI) and eye-tracking. Subjects visually tracked a point on a horizontal line in four conditions: time and position predictable task (PRED), posit...
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| description | Saccades were assessed in 21 adults (age 24 years, SD = 4) and 15 children (age 11 years, SD = 1), using combined functional magnetic resonance imaging (fMRI) and eye-tracking. Subjects visually tracked a point on a horizontal line in four conditions: time and position predictable task (PRED), position predictable (pPRED), time predictable (tPRED) and visually guided saccades (SAC). Both groups in the PRED but not in pPRED, tPRED and SAC produced predictive saccades with latency below 80 ms. In task versus group comparisons, children's showed less efficient learning compared to adults for predictive saccades (adults = 48%, children = 34%, p = 0.05). In adults brain activation was found in the frontal and occipital regions in the PRED, in the intraparietal sulcus in pPRED and in the frontal eye field, posterior intraparietal sulcus and medial regions in the tPRED task. Group-task interaction was found in the supplementary eye field and visual cortex in the PRED task, and the frontal cortex including the right frontal eye field and left frontal pole, in the pPRED condition. These results indicate that, the basic visuomotor circuitry is present in both adults and children, but fine-tuning of the activation according to the task temporal and spatial demand mature late in child development. |
| doi_str_mv | 10.1371/journal.pone.0196000 |
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Subjects visually tracked a point on a horizontal line in four conditions: time and position predictable task (PRED), position predictable (pPRED), time predictable (tPRED) and visually guided saccades (SAC). Both groups in the PRED but not in pPRED, tPRED and SAC produced predictive saccades with latency below 80 ms. In task versus group comparisons, children's showed less efficient learning compared to adults for predictive saccades (adults = 48%, children = 34%, p = 0.05). In adults brain activation was found in the frontal and occipital regions in the PRED, in the intraparietal sulcus in pPRED and in the frontal eye field, posterior intraparietal sulcus and medial regions in the tPRED task. Group-task interaction was found in the supplementary eye field and visual cortex in the PRED task, and the frontal cortex including the right frontal eye field and left frontal pole, in the pPRED condition. These results indicate that, the basic visuomotor circuitry is present in both adults and children, but fine-tuning of the activation according to the task temporal and spatial demand mature late in child development.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0196000</identifier><identifier>PMID: 29718927</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Activation ; Adult ; Adults ; Aging - physiology ; Analysis ; Behavior ; Biology and Life Sciences ; Brain ; Brain mapping ; Brain research ; Child ; Child development ; Children ; Circuits ; Cognition & reasoning ; Cortex (frontal) ; Cortex (occipital) ; Cortex (temporal) ; Eye ; Eye movements ; Female ; Functional magnetic resonance imaging ; Humans ; Image Processing, Computer-Assisted ; Intraparietal sulcus ; Latency ; Magnetic resonance ; Magnetic Resonance Imaging ; Male ; Medicine and Health Sciences ; Neuroimaging ; Neurosciences ; People and Places ; Physiological aspects ; Receptive field ; Research and Analysis Methods ; Saccades ; Saccades (Eye movements) ; Sensorimotor integration ; Social Sciences ; Studies ; Supplementary eye field ; Temporal lobe ; Time Factors ; Visual cortex ; Visual fields ; Young Adult</subject><ispartof>PloS one, 2018-05, Vol.13 (5), p.e0196000-e0196000</ispartof><rights>COPYRIGHT 2018 Public Library of Science</rights><rights>2018 Lukasova et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2018 Lukasova et al 2018 Lukasova et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-b5dfb0f62c07f4e2bc69ad42595c9b9e7aa9614510adbf2124413bfaaad91dc3</citedby><cites>FETCH-LOGICAL-c692t-b5dfb0f62c07f4e2bc69ad42595c9b9e7aa9614510adbf2124413bfaaad91dc3</cites><orcidid>0000-0002-1137-7298</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931500/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931500/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793,79600,79601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29718927$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Greenlee, Mark W.</contributor><creatorcontrib>Lukasova, Katerina</creatorcontrib><creatorcontrib>Nucci, Mariana P</creatorcontrib><creatorcontrib>Neto, Raymundo Machado de Azevedo</creatorcontrib><creatorcontrib>Vieira, Gilson</creatorcontrib><creatorcontrib>Sato, João R</creatorcontrib><creatorcontrib>Amaro, Jr, Edson</creatorcontrib><title>Predictive saccades in children and adults: A combined fMRI and eye tracking study</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Saccades were assessed in 21 adults (age 24 years, SD = 4) and 15 children (age 11 years, SD = 1), using combined functional magnetic resonance imaging (fMRI) and eye-tracking. Subjects visually tracked a point on a horizontal line in four conditions: time and position predictable task (PRED), position predictable (pPRED), time predictable (tPRED) and visually guided saccades (SAC). Both groups in the PRED but not in pPRED, tPRED and SAC produced predictive saccades with latency below 80 ms. In task versus group comparisons, children's showed less efficient learning compared to adults for predictive saccades (adults = 48%, children = 34%, p = 0.05). In adults brain activation was found in the frontal and occipital regions in the PRED, in the intraparietal sulcus in pPRED and in the frontal eye field, posterior intraparietal sulcus and medial regions in the tPRED task. Group-task interaction was found in the supplementary eye field and visual cortex in the PRED task, and the frontal cortex including the right frontal eye field and left frontal pole, in the pPRED condition. These results indicate that, the basic visuomotor circuitry is present in both adults and children, but fine-tuning of the activation according to the task temporal and spatial demand mature late in child development.</description><subject>Activation</subject><subject>Adult</subject><subject>Adults</subject><subject>Aging - physiology</subject><subject>Analysis</subject><subject>Behavior</subject><subject>Biology and Life Sciences</subject><subject>Brain</subject><subject>Brain mapping</subject><subject>Brain research</subject><subject>Child</subject><subject>Child development</subject><subject>Children</subject><subject>Circuits</subject><subject>Cognition & reasoning</subject><subject>Cortex (frontal)</subject><subject>Cortex (occipital)</subject><subject>Cortex (temporal)</subject><subject>Eye</subject><subject>Eye movements</subject><subject>Female</subject><subject>Functional magnetic resonance imaging</subject><subject>Humans</subject><subject>Image Processing, 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one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lukasova, Katerina</au><au>Nucci, Mariana P</au><au>Neto, Raymundo Machado de Azevedo</au><au>Vieira, Gilson</au><au>Sato, João R</au><au>Amaro, Jr, Edson</au><au>Greenlee, Mark W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictive saccades in children and adults: A combined fMRI and eye tracking study</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2018-05-02</date><risdate>2018</risdate><volume>13</volume><issue>5</issue><spage>e0196000</spage><epage>e0196000</epage><pages>e0196000-e0196000</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Saccades were assessed in 21 adults (age 24 years, SD = 4) and 15 children (age 11 years, SD = 1), using combined functional magnetic resonance imaging (fMRI) and eye-tracking. Subjects visually tracked a point on a horizontal line in four conditions: time and position predictable task (PRED), position predictable (pPRED), time predictable (tPRED) and visually guided saccades (SAC). Both groups in the PRED but not in pPRED, tPRED and SAC produced predictive saccades with latency below 80 ms. In task versus group comparisons, children's showed less efficient learning compared to adults for predictive saccades (adults = 48%, children = 34%, p = 0.05). In adults brain activation was found in the frontal and occipital regions in the PRED, in the intraparietal sulcus in pPRED and in the frontal eye field, posterior intraparietal sulcus and medial regions in the tPRED task. Group-task interaction was found in the supplementary eye field and visual cortex in the PRED task, and the frontal cortex including the right frontal eye field and left frontal pole, in the pPRED condition. These results indicate that, the basic visuomotor circuitry is present in both adults and children, but fine-tuning of the activation according to the task temporal and spatial demand mature late in child development.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>29718927</pmid><doi>10.1371/journal.pone.0196000</doi><orcidid>https://orcid.org/0000-0002-1137-7298</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Activation Adult Adults Aging - physiology Analysis Behavior Biology and Life Sciences Brain Brain mapping Brain research Child Child development Children Circuits Cognition & reasoning Cortex (frontal) Cortex (occipital) Cortex (temporal) Eye Eye movements Female Functional magnetic resonance imaging Humans Image Processing, Computer-Assisted Intraparietal sulcus Latency Magnetic resonance Magnetic Resonance Imaging Male Medicine and Health Sciences Neuroimaging Neurosciences People and Places Physiological aspects Receptive field Research and Analysis Methods Saccades Saccades (Eye movements) Sensorimotor integration Social Sciences Studies Supplementary eye field Temporal lobe Time Factors Visual cortex Visual fields Young Adult |
| title | Predictive saccades in children and adults: A combined fMRI and eye tracking study |
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