Development and evaluation of antibody-capture immunoassays for detection of Lassa virus nucleoprotein-specific immunoglobulin M and G

The classical method for detection of Lassa virus-specific antibodies is the immunofluorescence assay (IFA) using virus-infected cells as antigen. However, IFA requires laboratories of biosafety level 4 for assay production and an experienced investigator to interpret the fluorescence signals. There...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS neglected tropical diseases 2018-03, Vol.12 (3), p.e0006361-e0006361
Hauptverfasser:	Gabriel, Martin, Adomeh, Donatus I, Ehimuan, Jacqueline, Oyakhilome, Jennifer, Omomoh, Emmanuel O, Ighodalo, Yemisi, Olokor, Thomas, Bonney, Kofi, Pahlmann, Meike, Emmerich, Petra, Lelke, Michaela, Brunotte, Linda, Ölschläger, Stephan, Thomé-Bolduan, Corinna, Becker-Ziaja, Beate, Busch, Carola, Odia, Ikponmwosa, Ogbaini-Emovon, Ephraim, Okokhere, Peter O, Okogbenin, Sylvanus A, Akpede, George O, Schmitz, Herbert, Asogun, Danny A, Günther, Stephan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Assaying Biology and life sciences Biosafety Clinical trials Detection Diagnosis Diagnostic systems DNA ELISA Enzyme-linked immunosorbent assay Enzymes Epidemiology Evaluation Fc receptors Fever Fluorescence Genetic aspects IgG antibody Immune response Immunoassays Immunofluorescence Immunoglobulin G Immunoglobulin M Immunoglobulins Infections Laboratories Lassa fever Medical research Medicine Medicine and Health Sciences Methods Nucleotide sequence Patients PCR Polymerase chain reaction Receptors Recombinants Research and Analysis Methods Rheumatoid factor Specificity Supervision Teaching hospitals Tropical diseases Virology Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!