HIV prevalence by ethnic group covaries with prevalence of herpes simplex virus-2 and high-risk sex in Uganda: An ecological study
HIV prevalence varies from 1.7% to 14.8% between ethnic groups in Uganda. Understanding the factors responsible for this heterogeneity in HIV spread may guide prevention efforts. We evaluated the relationship between HIV prevalence by ethnic group and a range of risk factors as well as the prevalenc...
Gespeichert in:
| Veröffentlicht in: | PloS one 2018-04, Vol.13 (4), p.e0195431-e0195431 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0195431 |
|---|---|
| container_issue | 4 |
| container_start_page | e0195431 |
| container_title | PloS one |
| container_volume | 13 |
| creator | Kenyon, Chris R |
| description | HIV prevalence varies from 1.7% to 14.8% between ethnic groups in Uganda. Understanding the factors responsible for this heterogeneity in HIV spread may guide prevention efforts.
We evaluated the relationship between HIV prevalence by ethnic group and a range of risk factors as well as the prevalence of herpes simplex virus-2 (HSV-2), syphilis and symptomatic STIs in the 2004/2005 Uganda HIV/AIDS Sero-Behavioural Survey-a two stage, nationally representative, population based survey of 15-59-year-olds. Spearman's correlation was used to assess the relationship between HIV prevalence and each variable.
There was a positive association between HIV prevalence and HSV-2, symptomatic STIs and high-risk sex (sex with a non-cohabiting, non-marital partner) for women. Non-significant positive associations were present between HIV and high-risk sex for men and lifetime number of partners for men and women.
Variation in sexual behavior may contribute to the variations in HIV, HSV-2 and other STI prevalence by ethnic group in Uganda. Further work is necessary to delineate which combinations of risk factors determine differential STI spread in Uganda. |
| doi_str_mv | 10.1371/journal.pone.0195431 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2021716438</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A533366947</galeid><doaj_id>oai_doaj_org_article_fc8cd8268a1240648145d2c1899c6e78</doaj_id><sourcerecordid>A533366947</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-dfafe70ebc44450903859b4cb46bad802c132b12a6db83cd60cc5edfe066c123</originalsourceid><addsrcrecordid>eNqNk99v0zAQxyMEYmPwHyCwhITgocW_4jo8IFUTsEqTJsHYq-U4l8TDjYOdlPWVvxx37aYW7QH5wdbd5753Pvuy7CXBU8Jm5MO1H0On3bT3HUwxKXLOyKPsmBSMTgTF7PHe-Sh7FuM1xjmTQjzNjmghyIxTdpz9OVtcoT7ASjvoDKByjWBoO2tQE_zYI-NXOliI6Lcd2n3Q16iF0CdPtMvewQ1a2TDGCUW6q1Brm3YSbPyJYvLYDv1okll_RPMOgfHON9Zoh-IwVuvn2ZNauwgvdvtJdvnl8-Xp2eT84uvidH4-MaKgw6SqdQ0zDKXhnOe4wEzmRclNyUWpK4mpIYyWhGpRlZKZSmBjcqhqwEIYQtlJ9nor2zsf1a57UVFMyYwIzmQiFlui8vpa9cEudVgrr626NfjQKB0Gaxyo2khTSSqkJpRjwSXheZUqkEVhBMw2Wp922cZyCZWBbgjaHYgeejrbqsavVC4lz8Wm3Hc7geB_jRAHtbTRgHO6Az_e1k0Jw7LIE_rmH_Th2-2oJr2gsl3tU16zEVXznDEmRMFniZo-QKVVwdKa9NVqm-wHAe8PAhIzwM3Q6DFGtfj-7f_Zi6tD9u0e24J2Qxu9Gwfru3gI8i1ogo8xQH3fZILVZlLuuqE2k6J2k5LCXu0_0H3Q3Wiwv_fdDrU</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2021716438</pqid></control><display><type>article</type><title>HIV prevalence by ethnic group covaries with prevalence of herpes simplex virus-2 and high-risk sex in Uganda: An ecological study</title><source>Public Library of Science (PLoS) Journals Open Access</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Kenyon, Chris R</creator><creatorcontrib>Kenyon, Chris R</creatorcontrib><description>HIV prevalence varies from 1.7% to 14.8% between ethnic groups in Uganda. Understanding the factors responsible for this heterogeneity in HIV spread may guide prevention efforts.
We evaluated the relationship between HIV prevalence by ethnic group and a range of risk factors as well as the prevalence of herpes simplex virus-2 (HSV-2), syphilis and symptomatic STIs in the 2004/2005 Uganda HIV/AIDS Sero-Behavioural Survey-a two stage, nationally representative, population based survey of 15-59-year-olds. Spearman's correlation was used to assess the relationship between HIV prevalence and each variable.
There was a positive association between HIV prevalence and HSV-2, symptomatic STIs and high-risk sex (sex with a non-cohabiting, non-marital partner) for women. Non-significant positive associations were present between HIV and high-risk sex for men and lifetime number of partners for men and women.
Variation in sexual behavior may contribute to the variations in HIV, HSV-2 and other STI prevalence by ethnic group in Uganda. Further work is necessary to delineate which combinations of risk factors determine differential STI spread in Uganda.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0195431</identifier><identifier>PMID: 29617423</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Acquired immune deficiency syndrome ; AIDS ; Analysis ; Biology and Life Sciences ; Ecological risk assessment ; Ecological studies ; Environmental risk ; Epidemics ; Ethnic factors ; Health risk assessment ; Health risks ; Herpes simplex ; HIV ; HIV infections ; Human immunodeficiency virus ; Medicine and health sciences ; Minority & ethnic groups ; People and Places ; Prevalence studies (Epidemiology) ; Risk analysis ; Risk factors ; Sex ; Sexual behavior ; Sexually transmitted diseases ; STD ; Syphilis ; Systematic review ; Viruses</subject><ispartof>PloS one, 2018-04, Vol.13 (4), p.e0195431-e0195431</ispartof><rights>COPYRIGHT 2018 Public Library of Science</rights><rights>2018 Chris R. Kenyon. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2018 Chris R. Kenyon 2018 Chris R. Kenyon</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-dfafe70ebc44450903859b4cb46bad802c132b12a6db83cd60cc5edfe066c123</citedby><cites>FETCH-LOGICAL-c692t-dfafe70ebc44450903859b4cb46bad802c132b12a6db83cd60cc5edfe066c123</cites><orcidid>0000-0002-2557-8998</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884562/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884562/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79343,79344</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29617423$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kenyon, Chris R</creatorcontrib><title>HIV prevalence by ethnic group covaries with prevalence of herpes simplex virus-2 and high-risk sex in Uganda: An ecological study</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>HIV prevalence varies from 1.7% to 14.8% between ethnic groups in Uganda. Understanding the factors responsible for this heterogeneity in HIV spread may guide prevention efforts.
We evaluated the relationship between HIV prevalence by ethnic group and a range of risk factors as well as the prevalence of herpes simplex virus-2 (HSV-2), syphilis and symptomatic STIs in the 2004/2005 Uganda HIV/AIDS Sero-Behavioural Survey-a two stage, nationally representative, population based survey of 15-59-year-olds. Spearman's correlation was used to assess the relationship between HIV prevalence and each variable.
There was a positive association between HIV prevalence and HSV-2, symptomatic STIs and high-risk sex (sex with a non-cohabiting, non-marital partner) for women. Non-significant positive associations were present between HIV and high-risk sex for men and lifetime number of partners for men and women.
Variation in sexual behavior may contribute to the variations in HIV, HSV-2 and other STI prevalence by ethnic group in Uganda. Further work is necessary to delineate which combinations of risk factors determine differential STI spread in Uganda.</description><subject>Acquired immune deficiency syndrome</subject><subject>AIDS</subject><subject>Analysis</subject><subject>Biology and Life Sciences</subject><subject>Ecological risk assessment</subject><subject>Ecological studies</subject><subject>Environmental risk</subject><subject>Epidemics</subject><subject>Ethnic factors</subject><subject>Health risk assessment</subject><subject>Health risks</subject><subject>Herpes simplex</subject><subject>HIV</subject><subject>HIV infections</subject><subject>Human immunodeficiency virus</subject><subject>Medicine and health sciences</subject><subject>Minority & ethnic groups</subject><subject>People and Places</subject><subject>Prevalence studies (Epidemiology)</subject><subject>Risk analysis</subject><subject>Risk factors</subject><subject>Sex</subject><subject>Sexual behavior</subject><subject>Sexually transmitted diseases</subject><subject>STD</subject><subject>Syphilis</subject><subject>Systematic review</subject><subject>Viruses</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNk99v0zAQxyMEYmPwHyCwhITgocW_4jo8IFUTsEqTJsHYq-U4l8TDjYOdlPWVvxx37aYW7QH5wdbd5753Pvuy7CXBU8Jm5MO1H0On3bT3HUwxKXLOyKPsmBSMTgTF7PHe-Sh7FuM1xjmTQjzNjmghyIxTdpz9OVtcoT7ASjvoDKByjWBoO2tQE_zYI-NXOliI6Lcd2n3Q16iF0CdPtMvewQ1a2TDGCUW6q1Brm3YSbPyJYvLYDv1okll_RPMOgfHON9Zoh-IwVuvn2ZNauwgvdvtJdvnl8-Xp2eT84uvidH4-MaKgw6SqdQ0zDKXhnOe4wEzmRclNyUWpK4mpIYyWhGpRlZKZSmBjcqhqwEIYQtlJ9nor2zsf1a57UVFMyYwIzmQiFlui8vpa9cEudVgrr626NfjQKB0Gaxyo2khTSSqkJpRjwSXheZUqkEVhBMw2Wp922cZyCZWBbgjaHYgeejrbqsavVC4lz8Wm3Hc7geB_jRAHtbTRgHO6Az_e1k0Jw7LIE_rmH_Th2-2oJr2gsl3tU16zEVXznDEmRMFniZo-QKVVwdKa9NVqm-wHAe8PAhIzwM3Q6DFGtfj-7f_Zi6tD9u0e24J2Qxu9Gwfru3gI8i1ogo8xQH3fZILVZlLuuqE2k6J2k5LCXu0_0H3Q3Wiwv_fdDrU</recordid><startdate>20180404</startdate><enddate>20180404</enddate><creator>Kenyon, Chris R</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-2557-8998</orcidid></search><sort><creationdate>20180404</creationdate><title>HIV prevalence by ethnic group covaries with prevalence of herpes simplex virus-2 and high-risk sex in Uganda: An ecological study</title><author>Kenyon, Chris R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-dfafe70ebc44450903859b4cb46bad802c132b12a6db83cd60cc5edfe066c123</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>AIDS</topic><topic>Analysis</topic><topic>Biology and Life Sciences</topic><topic>Ecological risk assessment</topic><topic>Ecological studies</topic><topic>Environmental risk</topic><topic>Epidemics</topic><topic>Ethnic factors</topic><topic>Health risk assessment</topic><topic>Health risks</topic><topic>Herpes simplex</topic><topic>HIV</topic><topic>HIV infections</topic><topic>Human immunodeficiency virus</topic><topic>Medicine and health sciences</topic><topic>Minority & ethnic groups</topic><topic>People and Places</topic><topic>Prevalence studies (Epidemiology)</topic><topic>Risk analysis</topic><topic>Risk factors</topic><topic>Sex</topic><topic>Sexual behavior</topic><topic>Sexually transmitted diseases</topic><topic>STD</topic><topic>Syphilis</topic><topic>Systematic review</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kenyon, Chris R</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kenyon, Chris R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>HIV prevalence by ethnic group covaries with prevalence of herpes simplex virus-2 and high-risk sex in Uganda: An ecological study</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2018-04-04</date><risdate>2018</risdate><volume>13</volume><issue>4</issue><spage>e0195431</spage><epage>e0195431</epage><pages>e0195431-e0195431</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>HIV prevalence varies from 1.7% to 14.8% between ethnic groups in Uganda. Understanding the factors responsible for this heterogeneity in HIV spread may guide prevention efforts.
We evaluated the relationship between HIV prevalence by ethnic group and a range of risk factors as well as the prevalence of herpes simplex virus-2 (HSV-2), syphilis and symptomatic STIs in the 2004/2005 Uganda HIV/AIDS Sero-Behavioural Survey-a two stage, nationally representative, population based survey of 15-59-year-olds. Spearman's correlation was used to assess the relationship between HIV prevalence and each variable.
There was a positive association between HIV prevalence and HSV-2, symptomatic STIs and high-risk sex (sex with a non-cohabiting, non-marital partner) for women. Non-significant positive associations were present between HIV and high-risk sex for men and lifetime number of partners for men and women.
Variation in sexual behavior may contribute to the variations in HIV, HSV-2 and other STI prevalence by ethnic group in Uganda. Further work is necessary to delineate which combinations of risk factors determine differential STI spread in Uganda.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>29617423</pmid><doi>10.1371/journal.pone.0195431</doi><tpages>e0195431</tpages><orcidid>https://orcid.org/0000-0002-2557-8998</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2018-04, Vol.13 (4), p.e0195431-e0195431 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2021716438 |
| source | Public Library of Science (PLoS) Journals Open Access; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Acquired immune deficiency syndrome AIDS Analysis Biology and Life Sciences Ecological risk assessment Ecological studies Environmental risk Epidemics Ethnic factors Health risk assessment Health risks Herpes simplex HIV HIV infections Human immunodeficiency virus Medicine and health sciences Minority & ethnic groups People and Places Prevalence studies (Epidemiology) Risk analysis Risk factors Sex Sexual behavior Sexually transmitted diseases STD Syphilis Systematic review Viruses |
| title | HIV prevalence by ethnic group covaries with prevalence of herpes simplex virus-2 and high-risk sex in Uganda: An ecological study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T04%3A01%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=HIV%20prevalence%20by%20ethnic%20group%20covaries%20with%20prevalence%20of%20herpes%20simplex%20virus-2%20and%20high-risk%20sex%20in%20Uganda:%20An%20ecological%20study&rft.jtitle=PloS%20one&rft.au=Kenyon,%20Chris%20R&rft.date=2018-04-04&rft.volume=13&rft.issue=4&rft.spage=e0195431&rft.epage=e0195431&rft.pages=e0195431-e0195431&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0195431&rft_dat=%3Cgale_plos_%3EA533366947%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2021716438&rft_id=info:pmid/29617423&rft_galeid=A533366947&rft_doaj_id=oai_doaj_org_article_fc8cd8268a1240648145d2c1899c6e78&rfr_iscdi=true |