HIC1 links retinoic acid signalling to group 3 innate lymphoid cell-dependent regulation of intestinal immunity and homeostasis

The intestinal immune system must be able to respond to a wide variety of infectious organisms while maintaining tolerance to non-pathogenic microbes and food antigens. The Vitamin A metabolite all-trans-retinoic acid (atRA) has been implicated in the regulation of this balance, partially by regulat...

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Veröffentlicht in:	PLoS pathogens 2018-02, Vol.14 (2), p.e1006869-e1006869
Hauptverfasser:	Burrows, Kyle, Antignano, Frann, Chenery, Alistair, Bramhall, Michael, Korinek, Vladimir, Underhill, T Michael, Zaph, Colby
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Antigens Biochemistry Biology and Life Sciences Biomedical research Cancer Citrobacter Cytokines Dendritic cells Genetic aspects Health aspects Homeostasis Immune system Immunity Immunological tolerance Infections Inflammation Interleukin 22 Intestine Intestines Laboratories Medicine Medicine and Health Sciences Molecular biology Molecular modelling Pathology Physiological aspects Retinoic acid Signaling Transcription Transcription factors Tretinoin Tumor suppressor genes Vitamin A
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