Visualization and analysis of hepatitis C virus structural proteins at lipid droplets by super-resolution microscopy

Cytosolic lipid droplets are central organelles in the Hepatitis C Virus (HCV) life cycle. The viral capsid protein core localizes to lipid droplets and initiates the production of viral particles at lipid droplet-associated ER membranes. Core is thought to encapsidate newly synthesized viral RNA an...

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Veröffentlicht in:	PloS one 2014-07, Vol.9 (7), p.e102511-e102511
Hauptverfasser:	Eggert, Dennis, Rösch, Kathrin, Reimer, Rudolph, Herker, Eva
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology and life sciences Capsid protein Droplets Hepacivirus - metabolism Hepatitis Hepatitis C Hepatitis C virus Infections Lasers Life cycle engineering Life cycles Lipid Droplets - ultrastructure Lipid Droplets - virology Lipids Membranes Microscopy Microscopy, Confocal Microscopy, Fluorescence - methods Organelles Proteins Research and Analysis Methods Ribonucleic acid RNA Spatial distribution Structural proteins Viral infections Viral Structural Proteins - chemistry Viral Structural Proteins - metabolism Viral Structural Proteins - ultrastructure Virology Viruses
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