The ARID1A, p53 and ß-Catenin statuses are strong prognosticators in clear cell and endometrioid carcinoma of the ovary and the endometrium

The objective of this study was to evaluate the prognostic value of ARID1A, p53, p21, p16 and ß-Catenin in endometrioid and clear cell ovarian and endometrial carcinomas. 97 tumors were available for analysis of ARID1A, p53, p21, p16 and ß-Catenin with the techniques of tissue microarray and immunoh...

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Veröffentlicht in:	PloS one 2018-02, Vol.13 (2), p.e0192881-e0192881
Hauptverfasser:	Heckl, Marlene, Schmoeckel, Elisa, Hertlein, Linda, Rottmann, Miriam, Jeschke, Udo, Mayr, Doris
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Adenocarcinoma, Clear Cell - metabolism Adenocarcinoma, Clear Cell - pathology Adult Aged Aged, 80 and over Analysis beta Catenin - metabolism Biology and Life Sciences Biomarkers, Tumor - metabolism Cancer Carcinoma, Ovarian Epithelial Catenin Cell cycle Cyclin-dependent kinase inhibitor p21 Development and progression Endometrial cancer Endometrial Neoplasms - metabolism Endometrial Neoplasms - pathology Endometrium Female Gastric cancer Gene Expression Regulation, Neoplastic Genetic aspects Gynecological cancer Gynecology Humans Immunohistochemistry Kinases Medical prognosis Medicine and Health Sciences Middle Aged Mutation Neoplasms, Glandular and Epithelial - metabolism Neoplasms, Glandular and Epithelial - pathology Nuclear Proteins - metabolism Obstetrics Ovarian cancer Ovarian carcinoma Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology p53 Protein Pathogenesis Pathology Physical characteristics Physiological aspects Prognosis Proteins Regression analysis Research and Analysis Methods Staining Stomach cancer Studies Subgroups Survival Rate Transcription Factors - metabolism Tumor proteins Tumor suppressor genes Tumor Suppressor Protein p53 - metabolism Tumors Uterine cancer Uterine Neoplasms - metabolism Uterine Neoplasms - pathology Uterus
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