Regulation of circadian clock transcriptional output by CLOCK:BMAL1

The mammalian circadian clock relies on the transcription factor CLOCK:BMAL1 to coordinate the rhythmic expression of 15% of the transcriptome and control the daily regulation of biological functions. The recent characterization of CLOCK:BMAL1 cistrome revealed that although CLOCK:BMAL1 binds synchr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS genetics 2018-01, Vol.14 (1), p.e1007156-e1007156
Hauptverfasser:	Trott, Alexandra J, Menet, Jerome S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ARNTL Transcription Factors - metabolism ARNTL Transcription Factors - physiology Binding sites Binding Sites - genetics Biological clocks Biology and life sciences BMAL1 protein Cellular biology Chromatin Circadian Clocks - genetics Circadian rhythm Circadian Rhythm - genetics Circadian rhythms CLOCK Proteins - metabolism CLOCK Proteins - physiology Datasets Deoxyribonucleic acid DNA DNA methylation DNA-directed RNA polymerase Enhancer Elements, Genetic - genetics Enhancers Enzymes Gene expression Gene Expression Regulation Gene regulation Genetic aspects Genomes Inflammation Mice Observations Protein Binding Proteins RNA polymerase Transcription (Genetics) Transcription activation Transcription factors Transcription, Genetic
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!