Assessment of serum pharmacokinetics and urinary excretion of albendazole and its metabolites in human volunteers

Soil Transmitted Helminth (STH) infections negatively impact physical and mental development in human populations. Current WHO guidelines recommend morbidity control of these infections through mass drug administration (MDA) using albendazole (ABZ) or mebendazole. Despite major reductions in STH ass...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS neglected tropical diseases 2018-01, Vol.12 (1), p.e0005945-e0005945
Hauptverfasser:	Ceballos, Laura, Krolewiecki, Alejandro, Juárez, Marisa, Moreno, Laura, Schaer, Fabian, Alvarez, Luis I, Cimino, Rubén, Walson, Judd, Lanusse, Carlos E
Format:	Artikel
Sprache:	eng
Schlagworte:	Albendazole Ancylostoma duodenale Ascaris lumbricoides Biology and Life Sciences Blood serum Chemical kinetics Data recovery Dosage and administration Drug therapy Drugs Duration Excretion Failures Funding Health aspects High-performance liquid chromatography HPLC Human populations Infections Kinetics Liquid chromatography Mebendazole Medicine and Health Sciences Mental development Metabolism Metabolites Morbidity Museums Necator americanus Optimization Oral administration Parasites Pharmacokinetics Pharmacology Physical Sciences Reaction kinetics Recovery Research and Analysis Methods Roundworm infections Samples Sanitation Serum Soil Sulfoxides Trichuris trichiura Tropical diseases Urine Youth volunteers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!