The WHO 2016 verbal autopsy instrument: An international standard suitable for automated analysis by InterVA, InSilicoVA, and Tariff 2.0

Verbal autopsy (VA) is a practical method for determining probable causes of death at the population level in places where systems for medical certification of cause of death are weak. VA methods suitable for use in routine settings, such as civil registration and vital statistics (CRVS) systems, ha...

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Veröffentlicht in:PLoS medicine 2018-01, Vol.15 (1), p.e1002486-e1002486
Hauptverfasser: Nichols, Erin K, Byass, Peter, Chandramohan, Daniel, Clark, Samuel J, Flaxman, Abraham D, Jakob, Robert, Leitao, Jordana, Maire, Nicolas, Rao, Chalapati, Riley, Ian, Setel, Philip W
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container_title PLoS medicine
container_volume 15
creator Nichols, Erin K
Byass, Peter
Chandramohan, Daniel
Clark, Samuel J
Flaxman, Abraham D
Jakob, Robert
Leitao, Jordana
Maire, Nicolas
Rao, Chalapati
Riley, Ian
Setel, Philip W
description Verbal autopsy (VA) is a practical method for determining probable causes of death at the population level in places where systems for medical certification of cause of death are weak. VA methods suitable for use in routine settings, such as civil registration and vital statistics (CRVS) systems, have developed rapidly in the last decade. These developments have been part of a growing global momentum to strengthen CRVS systems in low-income countries. With this momentum have come pressure for continued research and development of VA methods and the need for a single standard VA instrument on which multiple automated diagnostic methods can be developed. In 2016, partners harmonized a WHO VA standard instrument that fully incorporates the indicators necessary to run currently available automated diagnostic algorithms. The WHO 2016 VA instrument, together with validated approaches to analyzing VA data, offers countries solutions to improving information about patterns of cause-specific mortality. This VA instrument offers the opportunity to harmonize the automated diagnostic algorithms in the future. Despite all improvements in design and technology, VA is only recommended where medical certification of cause of death is not possible. The method can nevertheless provide sufficient information to guide public health priorities in communities in which physician certification of deaths is largely unavailable. The WHO 2016 VA instrument, together with validated approaches to analyzing VA data, offers countries solutions to improving information about patterns of cause-specific mortality.
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VA methods suitable for use in routine settings, such as civil registration and vital statistics (CRVS) systems, have developed rapidly in the last decade. These developments have been part of a growing global momentum to strengthen CRVS systems in low-income countries. With this momentum have come pressure for continued research and development of VA methods and the need for a single standard VA instrument on which multiple automated diagnostic methods can be developed. In 2016, partners harmonized a WHO VA standard instrument that fully incorporates the indicators necessary to run currently available automated diagnostic algorithms. The WHO 2016 VA instrument, together with validated approaches to analyzing VA data, offers countries solutions to improving information about patterns of cause-specific mortality. This VA instrument offers the opportunity to harmonize the automated diagnostic algorithms in the future. 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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Nichols EK, Byass P, Chandramohan D, Clark SJ, Flaxman AD, Jakob R, et al. (2018) The WHO 2016 verbal autopsy instrument: An international standard suitable for automated analysis by InterVA, InSilicoVA, and Tariff 2.0. PLoS Med 15(1): e1002486. https://doi.org/10.1371/journal.pmed.1002486</rights><rights>2018 World Health Organization 2018 World Health Organization</rights><rights>2018 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Nichols EK, Byass P, Chandramohan D, Clark SJ, Flaxman AD, Jakob R, et al. (2018) The WHO 2016 verbal autopsy instrument: An international standard suitable for automated analysis by InterVA, InSilicoVA, and Tariff 2.0. 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VA methods suitable for use in routine settings, such as civil registration and vital statistics (CRVS) systems, have developed rapidly in the last decade. These developments have been part of a growing global momentum to strengthen CRVS systems in low-income countries. With this momentum have come pressure for continued research and development of VA methods and the need for a single standard VA instrument on which multiple automated diagnostic methods can be developed. In 2016, partners harmonized a WHO VA standard instrument that fully incorporates the indicators necessary to run currently available automated diagnostic algorithms. The WHO 2016 VA instrument, together with validated approaches to analyzing VA data, offers countries solutions to improving information about patterns of cause-specific mortality. This VA instrument offers the opportunity to harmonize the automated diagnostic algorithms in the future. Despite all improvements in design and technology, VA is only recommended where medical certification of cause of death is not possible. The method can nevertheless provide sufficient information to guide public health priorities in communities in which physician certification of deaths is largely unavailable. The WHO 2016 VA instrument, together with validated approaches to analyzing VA data, offers countries solutions to improving information about patterns of cause-specific mortality.</description><subject>Algorithms</subject><subject>Automation</subject><subject>Autopsies</subject><subject>Autopsy</subject><subject>Autopsy - methods</subject><subject>Autopsy - standards</subject><subject>Cause of Death</subject><subject>Certification</subject><subject>Computer and Information Sciences</subject><subject>Data processing</subject><subject>Death</subject><subject>Engineering and Technology</subject><subject>Epidemiology</subject><subject>Guidelines and Guidance</subject><subject>Health sciences</subject><subject>Health surveillance</subject><subject>Humans</subject><subject>Hygiene</subject><subject>Innovations</subject><subject>Medical research</subject><subject>Medical technology</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Methods</subject><subject>Mortality</subject><subject>People and Places</subject><subject>Physical Sciences</subject><subject>Population</subject><subject>Public health</subject><subject>R&amp;D</subject><subject>Research &amp; development</subject><subject>Research and Analysis Methods</subject><subject>Statistical analysis</subject><subject>Studies</subject><subject>Tariffs</subject><subject>Technology application</subject><subject>Vital Statistics</subject><subject>Working groups</subject><subject>World Health Organization</subject><issn>1549-1676</issn><issn>1549-1277</issn><issn>1549-1676</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>D8T</sourceid><sourceid>DOA</sourceid><recordid>eNqVk99u0zAUxiMEYmPwBggsTUIg0WI7sRNzgVSNP6s0MYmNcWmdOE7rKYmL7Qz6Bjw2ztqNBu0ClIvYzu_7zvE5OUnylOApSXPy5tL2roNmump1NSUY06zg95J9wjIxITzn93fWe8kj7y8jI7DAD5M9KlKKM8H2k1_nS42-HZ8iiglHV9qV0CDog135NTKdD65vdRfeolkXt0HHkMHYGBf5AF0FrkK-NwHKRqPaumtpC0FXCCK09sajco3mg_Ji9jouzkxjlB3WUY7OwZm6RnSKHycPami8frJ9HyRfP344PzqenJx-mh_NTiaq4EWYUCpyWpclAKsF4yzXlIu81AVwnWNVMgEsS6GK-6xiaZqXVV2xWgGUPBeCpgfJ843vqrFebovoJY3F4aSgOY7EfENUFi7lypkW3FpaMPL6wLqFBBeMarQkqcIiVYzXhcgwSUVRM6i4ECBUUak8ek02Xv6HXvXlyO29uZhdu_VtL0kW28Ei_26bXV_GvqpYegfNSDb-0pmlXNgryfIh-yIavNwaOPu91z7I1nilmwY6bXsviShi2UiRioge_oXeXY0ttYB4YdPVNsZVg6mcMcoE4UWa_bnniFroTsckbadrE49H_PQOPj6VbuPvcZfg1UgQmaB_hgX03sv52Zf_YD__O3t6MWZf7LBLDU1Yetv0w0D4MZhtQOWs907Xtw0kWA7De1NpOQyv3A5vlD3bbf6t6GZa098YFD0q</recordid><startdate>20180110</startdate><enddate>20180110</enddate><creator>Nichols, Erin K</creator><creator>Byass, Peter</creator><creator>Chandramohan, Daniel</creator><creator>Clark, Samuel J</creator><creator>Flaxman, Abraham D</creator><creator>Jakob, Robert</creator><creator>Leitao, Jordana</creator><creator>Maire, Nicolas</creator><creator>Rao, Chalapati</creator><creator>Riley, Ian</creator><creator>Setel, Philip W</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISN</scope><scope>ISR</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>ADHXS</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>D8T</scope><scope>D93</scope><scope>ZZAVC</scope><scope>DOA</scope><scope>CZK</scope><orcidid>https://orcid.org/0000-0002-4917-1412</orcidid><orcidid>https://orcid.org/0000-0001-5474-4361</orcidid><orcidid>https://orcid.org/0000-0002-1961-9343</orcidid><orcidid>https://orcid.org/0000-0001-6033-4713</orcidid></search><sort><creationdate>20180110</creationdate><title>The WHO 2016 verbal autopsy instrument: An international standard suitable for automated analysis by InterVA, InSilicoVA, and Tariff 2.0</title><author>Nichols, Erin K ; 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subjects Algorithms
Automation
Autopsies
Autopsy
Autopsy - methods
Autopsy - standards
Cause of Death
Certification
Computer and Information Sciences
Data processing
Death
Engineering and Technology
Epidemiology
Guidelines and Guidance
Health sciences
Health surveillance
Humans
Hygiene
Innovations
Medical research
Medical technology
Medicine
Medicine and Health Sciences
Methods
Mortality
People and Places
Physical Sciences
Population
Public health
R&D
Research & development
Research and Analysis Methods
Statistical analysis
Studies
Tariffs
Technology application
Vital Statistics
Working groups
World Health Organization
title The WHO 2016 verbal autopsy instrument: An international standard suitable for automated analysis by InterVA, InSilicoVA, and Tariff 2.0
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