Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers

Ivermectin is a pivotal drug for the control of onchocerciasis and lymphatic filariasis, which is increasingly identified as a useful drug for the control of other Neglected Tropical Diseases. Its role in the treatment of soil transmitted helminthiasis through improved efficacy against Trichuris tri...

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Veröffentlicht in:	PLoS neglected tropical diseases 2018-01, Vol.12 (1), p.e0006020-e0006020
Hauptverfasser:	Muñoz, Jose, Ballester, Maria Rosa, Antonijoan, Rosa Maria, Gich, Ignasi, Rodríguez, Montse, Colli, Enrico, Gold, Silvia, Krolewiecki, Alejandro J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Administració de medicaments Administration of drugs Anthelmintic agents Antiparasitic agents Avermectin Bioavailability Biology and Life Sciences Body mass Body mass index Body size Body weight Dosage Dosage and administration Drug dosages Drug therapy Drugs Farmacocinètica Filariasis Funding Headache Health aspects Helminthiasis High-performance liquid chromatography Homology Hospitals HPLC Ivermectin Liquid chromatography Malaria Medical treatment Medicine and Health Sciences Onchocerca volvulus Onchocerciasis Parameters Pharmacokinetics Pharmacology Research and Analysis Methods Safety Safety and security measures Soil Soil improvement Soil treatment Tissue Transmission Tropical climate Tropical diseases Uses Vector-borne diseases Weight Youth volunteers
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