Quick and easy sample preparation without resin embedding for the bone quality assessment of fresh calcified bone using fourier transform infrared imaging

Fourier transform infrared (FTIR) imaging is a powerful tool for the assessment of bone quality; however, it requires the preparation of thin bone sections. Conventional poly(methyl methacrylate) (PMMA) embedding for the preparation of sections takes more than two weeks and causes denaturation of th...

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Veröffentlicht in:	PloS one 2018-02, Vol.13 (2), p.e0189650-e0189650
Hauptverfasser:	Kimura-Suda, Hiromi, Takahata, Masahiko, Ito, Teppei, Shimizu, Tomohiro, Kanazawa, Kyosuke, Ota, Masahiro, Iwasaki, Norimasa
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical chemistry Anisotropy Biology and Life Sciences Bone imaging Bone surgery Calcification Carbonates Care and treatment Collagen Corrosion resistance Crystal structure Crystallinity Dehydration Denaturation Discriminant analysis Embedding Femur Fourier transforms Heat shock Histology Hydroxyapatite Infrared imaging Infrared spectroscopy Medicine Medicine and Health Sciences Mineralization Orthopedics Osteoporosis Phosphates Photonics Physical Sciences Polymethyl methacrylate Polymethylmethacrylate Polypropylene Proteins Quality Quality assessment Quality control Research and Analysis Methods Sample preparation Sectioning Shock resistance Substrates
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