Phytochemical characterization of the Vochysia rufa (Vochysiaceae) extract and its effects on oxidative stress in the pancreata of streptozotocin-induced diabetic rats

Aqueous extract of macerated Vochysia rufa stem bark has been commonly used in the treatment of diabetes. Therefore, we evaluated the antihyperglycemic and antioxidant effects of an extract of V. rufa on the pancreata of streptozotocin (STZ)-induced diabetic rats. Animals received one of the followi...

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Veröffentlicht in:	PloS one 2017-10, Vol.12 (10), p.e0184807-e0184807
Hauptverfasser:	de Gouveia, Neire M, Rodrigues, Wellington F, de Sousa, Raquel M F, Calábria, Luciana K, Mundim, Antonio V, Miguel, Camila B, Oliveira, Carlo J F, Lazo-Chica, Javier E, de Oliveira, Alberto, Lago, João H G, Dos Santos, Vagner B, do Lago, Claudimir L, Espindola, Foued S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Adenosine triphosphatase Animals Antioxidants Antioxidants - pharmacology Arabinose Bark Biochemical analysis Biology and Life Sciences Blood Blood Glucose Body Weight - drug effects Care and treatment Catalase Catalase - metabolism Chemical properties Cholesterol Creatinine Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - metabolism Enzymes Galactose Glibenclamide Glucose Glutathione Glutathione - metabolism Glutathione peroxidase High density lipoprotein Immunohistochemistry Inositol Insulin Magnoliopsida Male Mannose Medicine and Health Sciences Metabolites Oxidative stress Oxidative Stress - drug effects Pancreas Pancreas - drug effects Pancreas - metabolism Peroxidase Physical Sciences Phytochemicals Phytotherapy Plant Extracts - pharmacology Rats Rats, Wistar Ribose Rodents Sucrose Sugar Superoxide dismutase Superoxide Dismutase - metabolism Thiobarbituric acid Thiobarbituric Acid Reactive Substances - metabolism Triglycerides Urea Vochysiaceae Water treatment
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