Effects of preoperative aspirin on perioperative platelet activation and dysfunction in patients undergoing off-pump coronary artery bypass graft surgery: A prospective randomized study

The benefit of aspirin use after coronary artery bypass graft surgery has been well proven. However, the effect of preoperative aspirin use in patients undergoing off-pump coronary artery bypass graft surgery (OPCAB) has not been evaluated sufficiently. To evaluate platelet function changes during O...

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Veröffentlicht in:	PloS one 2017-07, Vol.12 (7), p.e0180466-e0180466
Hauptverfasser:	Lee, Jiwon, Jung, Chul-Woo, Jeon, Yunseok, Kim, Tae Kyong, Cho, Youn Joung, Koo, Chang-Hoon, Choi, Yoon Hyeong, Kim, Ki-Bong, Hwang, Ho Young, Kim, Hang-Rae, Park, Ji-Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Activation Aged Agglomeration Analysis Anesthesia Anesthesiology Anticoagulants Arachidonic acid Aspirin Aspirin - pharmacology Biology and Life Sciences Bleeding Blood platelets Blood Platelets - drug effects Blood Platelets - physiology Bypasses CD63 antigen Clinical trials Coagulation Complications and side effects Coronary artery Coronary artery bypass Coronary Artery Bypass, Off-Pump - adverse effects Coronary vessels Cytometry Dosage and administration Female Flow cytometry Grafting Heart surgery Hemorrhage - etiology Hemorrhage - physiopathology Hospitals Humans Male Medicine Medicine and Health Sciences Methods PAC1 protein Pain Patient outcomes Patients Physicians Physiological aspects Platelet Activation - drug effects Platelet aggregation Platelet Aggregation Inhibitors - pharmacology Preoperative Period Prospective Studies Pulmonary arteries Randomization Research and Analysis Methods Surgery Systematic review Transfusion Veins & arteries
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