NF-kappa B activation correlates with disease phenotype in Crohn's disease

Unregulated activation of nuclear factor-κB (NF-κB) plays a critical role in the pathogenesis of Crohn's disease. In this study, we investigated the clinical characteristics and disease outcome of Crohn's disease patients with varying levels of the NF-κB activation. Crohn's disease pa...

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Veröffentlicht in:	PloS one 2017-07, Vol.12 (7), p.e0182071-e0182071
Hauptverfasser:	Han, Yoo Min, Koh, Jaemoon, Kim, Ji Won, Lee, Changhyun, Koh, Seong-Joon, Kim, ByeongGwan, Lee, Kook Lae, Im, Jong Pil, Kim, Joo Sung
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Adolescent Adult Biology and Life Sciences Colon - metabolism Colon - pathology Crohn Disease - metabolism Crohn Disease - pathology Crohn's disease Crohns disease Demographics Drugs Family medical history Female Gastroenterology Genetic aspects Genotype & phenotype Hospitals Humans Immunohistochemistry Immunoreactivity Inflammatory bowel disease Internal medicine Intestine Intestines - metabolism Intestines - physiology Male Medical prognosis Medical records Medicine Medicine and Health Sciences Middle Aged NF-kappa B - metabolism NF-κB protein Pathogenesis Pathology Patients Phenotypes Research and Analysis Methods Studies Surgery Systematic review Tissue Array Analysis Young Adult
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