Modulation of HIV replication in monocyte derived macrophages (MDM) by steroid hormones

Significant sex specific differences in the progression of HIV/AIDS have been reported. Several studies have implicated steroid hormones in regulating host factor expression and modulating HIV transmission and replication. However, the exact mechanism exerted by steroid hormones estrogen and progest...

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Veröffentlicht in:	PloS one 2018-01, Vol.13 (1), p.e0191916-e0191916
Hauptverfasser:	Devadas, Krishnakumar, Biswas, Santanu, Ragupathy, Viswanath, Lee, Sherwin, Dayton, Andrew, Hewlett, Indira
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome AIDS Antiviral agents Biology and Life Sciences Cell culture Chemokines Correlation analysis CXCL10 protein CXCL11 protein Cytokines Disease transmission Estrogens Gene expression Genes Genetic aspects HIV Hormones Human immunodeficiency virus Inflammation Inflammatory response Interferon Interleukin 6 Low concentrations Macrophages Medicine and Health Sciences Modulation Molecular modelling Monocytes Polymerase chain reaction Progesterone Replication Sex Sexually transmitted diseases Signaling STD Steroid hormones Studies Transcription factors Virus replication
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