A selected reaction monitoring mass spectrometric assessment of biomarker candidates diagnosing large-cell neuroendocrine lung carcinoma by the scaling method using endogenous references

Selected reaction monitoring mass spectrometry (SRM-MS) -based semi-quantitation was performed to assess the validity of 46 selected candidate proteins for specifically diagnosing large-cell neuroendocrine lung carcinoma (LCNEC) and differentiating it from other lung cancer subtypes. The scaling met...

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Veröffentlicht in:	PloS one 2017-04, Vol.12 (4), p.e0176219-e0176219
Hauptverfasser:	Fukuda, Tetsuya, Nomura, Masaharu, Kato, Yasufumi, Tojo, Hiromasa, Fujii, Kiyonaga, Nagao, Toshitaka, Bando, Yasuhiko, Fehniger, Thomas E, Marko-Varga, György, Nakamura, Haruhiko, Kato, Harubumi, Nishimura, Toshihide
Format:	Artikel
Sprache:	eng
Schlagworte:	Apolipoprotein A Apolipoprotein A-I Apolipoproteins Biology and Life Sciences Biomarkers Biomarkers, Tumor - metabolism Biomedical engineering Brain Carcinoma, Large Cell - diagnosis Carcinoma, Large Cell - metabolism Carcinoma, Neuroendocrine - diagnosis Carcinoma, Neuroendocrine - metabolism Cell surface Chromatography Creatine Creatine kinase Dehydrogenases Galectin-3 Humans Informatics Lung cancer Lung carcinoma Lung diseases Lung Neoplasms - diagnosis Lung Neoplasms - metabolism Mass Spectrometry Mass spectroscopy Medical and Health Sciences Medical Biotechnology Medical diagnosis Medicin och hälsovetenskap Medicine Medicine and Health Sciences Medicinsk bioteknologi Monitoring Peptides Phosphatidylethanolamine Phosphopyruvate hydratase Proteins Proteomics - methods Proteomics - standards Quantitation Reference Standards Research and Analysis Methods Retina Retinaldehyde dehydrogenase Scaling Scientific imaging Small cell lung carcinoma Statistical analysis Stem cells Studies Surgery Thoracic surgery Thyroid gland Tumors Variance analysis
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