RNA interference in Fasciola gigantica: Establishing and optimization of experimental RNAi in the newly excysted juveniles of the fluke

Fasciolosis caused by Fasciola gigantica is a neglected tropical disease but a constraint on the growth and productivity of cattle, buffaloes and sheep in the tropical countries of Asia and Africa. Resistance to commonly used anthelmintics in Fasciola has increased the need to search for alternative...

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Veröffentlicht in:	PLoS neglected tropical diseases 2017-12, Vol.11 (12), p.e0006109-e0006109
Hauptverfasser:	Anandanarayanan, Arun, Raina, Opinder Krishen, Lalrinkima, Hniang, Rialch, Ajayta, Sankar, Muthu, Varghese, Anju
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal sciences Anthelmintic agents Biology and life sciences Buffalo Cattle Double-stranded RNA Fasciola Fasciola gigantica Fasciola hepatica Gene expression Gene silencing Genes Glutathione transferase Health aspects Interference Juveniles Liver Livestock Methods Optimization Parasites Parasitology Proteins Research and Analysis Methods Ribonucleic acid Ribosomal DNA RNA RNA interference RNA-mediated interference Schistosoma mansoni Sheep siRNA Software Studies Superoxide dismutase Target detection Tropical diseases Vaccines Zoonoses
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