The Effects of Acute Neutrophil Depletion on Resolution of Acute Influenza Infection, Establishment of Tissue Resident Memory (TRM), and Heterosubtypic Immunity

After disease resolution, a small subset of influenza specific CD8+ T cells can remain in the airways of the lung as a tissue resident memory population (TRM). These cells are critical for protection from subsequent infections with heterosubtypic influenza viruses. Although it is well established th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2016-10, Vol.11 (10), p.e0164247-e0164247
Hauptverfasser:	Reilly, Emma C, Lambert-Emo, Kris, Topham, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Antibodies - immunology Antibodies - pharmacology Antigens Biology Biology and Life Sciences Bronchoalveolar Lavage Fluid - cytology Bronchoalveolar Lavage Fluid - immunology CD8 antigen CD8-Positive T-Lymphocytes - cytology CD8-Positive T-Lymphocytes - immunology Collagen Collagen (type IV) CXCL12 protein Cytokines Depletion Dogs Health aspects Immunity Immunologic Memory - physiology Immunological memory Immunology Infections Influenza Influenza A Virus, H1N1 Subtype - pathogenicity Influenza A Virus, H3N2 Subtype - metabolism Influenza A Virus, H3N2 Subtype - pathogenicity Influenza viruses Integrin alpha Chains - immunology Leukocytes (neutrophilic) Lung - cytology Lung - immunology Lung - virology Lungs Lymphocytes Lymphocytes T Madin Darby Canine Kidney Cells Medicine and Health Sciences Mice Mice, Inbred C57BL Microscopy, Fluorescence Neutrophils Neutrophils - cytology Neutrophils - drug effects Orthomyxoviridae Orthomyxoviridae Infections - immunology Orthomyxoviridae Infections - pathology Population Research and Analysis Methods Retention T cells Vaccines Viral Load Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!