Use of Cepheid Xpert Carba-R® for Rapid Detection of Carbapenemase-Producing Bacteria in Abdominal Septic Patients Admitted to Intensive Care Unit

Early institution of effective antibiotic therapy and source control are pivotal to improve survival of abdominal septic patients. Xpert® Carba-R is a real time polymerase chain reaction assay for rapid detection and differentiation of five genes (blaKPC, blaVIM, blaOXA-48, blaIMP-1, blaNDM) respons...

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Veröffentlicht in:	PloS one 2016-08, Vol.11 (8), p.e0160643-e0160643
Hauptverfasser:	Cortegiani, Andrea, Russotto, Vincenzo, Graziano, Giorgio, Geraci, Daniela, Saporito, Laura, Cocorullo, Gianfranco, Raineri, Santi Maurizio, Mammina, Caterina, Giarratano, Antonino
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Abdomen - microbiology Abdominal surgery Aged Antibiotics Antimicrobial agents Bacteria Bacterial Proteins - metabolism beta-Lactamases - metabolism Biology and Life Sciences Carbapenemase Carbapenems - pharmacology Care and treatment Causes of Chemotherapy Child care Critical care Diagnostic software Diagnostic systems DNA, Bacterial - isolation & purification DNA, Bacterial - metabolism Drug resistance Drug Resistance, Bacterial - drug effects Drug Resistance, Bacterial - genetics Enterobacteriaceae Enterobacteriaceae - enzymology Enterobacteriaceae - genetics Enterobacteriaceae - isolation & purification Epidemiology Female Genes Gram-negative bacteria Health aspects Health promotion Hospitals Humans Infections Infectious diseases Intensive care Intensive Care Units Laboratories Male Medical diagnosis Medicine and Health Sciences Microbiological culture Microbiology Microorganisms Middle Aged Patients Polymerase chain reaction Reagent Kits, Diagnostic Real-Time Polymerase Chain Reaction Rectum Rectum - microbiology Research and Analysis Methods Sensitivity Sensitivity and Specificity Sepsis Sepsis - diagnosis Sepsis - microbiology
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