Loss of Gravitropism in Farnesene-Treated Arabidopsis Is Due to Microtubule Malformations Related to Hormonal and ROS Unbalance
Mode of action of farnesene, a volatile sesquiterpene commonly found in the essential oils of several plants, was deeply studied on the model species Arabidopsis thaliana. The effects of farnesene on the Arabidopsis root morphology were evaluated by different microscopic techniques. As well, microtu...
Gespeichert in:
| Veröffentlicht in: | PloS one 2016-08, Vol.11 (8), p.e0160202-e0160202 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0160202 |
|---|---|
| container_issue | 8 |
| container_start_page | e0160202 |
| container_title | PloS one |
| container_volume | 11 |
| creator | Araniti, Fabrizio Graña, Elisa Krasuska, Urszula Bogatek, Renata Reigosa, Manuel J Abenavoli, Maria Rosa Sánchez-Moreiras, Adela M |
| description | Mode of action of farnesene, a volatile sesquiterpene commonly found in the essential oils of several plants, was deeply studied on the model species Arabidopsis thaliana. The effects of farnesene on the Arabidopsis root morphology were evaluated by different microscopic techniques. As well, microtubules immunolabeling, phytohormone measurements and ROS staining helped us to elucidate the single or multi-modes of action of this sesquiterpene on plant metabolism. Farnesene-treated roots showed a strong growth inhibition and marked modifications on morphology, important tissue alterations, cellular damages and anisotropic growth. Left-handed growth of farnesene-treated roots, reverted by taxol (a known microtubule stabilizer), was related to microtubule condensation and disorganization. As well, the inhibition of primary root growth, lateral root number, lateral root length, and both root hairs length and density could be explained by the strong increment in ethylene production and auxin content detected in farnesene-treated seedlings. Microtubule alteration and hormonal unbalance appear as important components in the mode of action of farnesene and confirm the strong phytotoxic potential of this sesquiterpene. |
| doi_str_mv | 10.1371/journal.pone.0160202 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1987352355</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A459945214</galeid><doaj_id>oai_doaj_org_article_e8f3af4d5f6448b9bf3b8cda6ed6d5ae</doaj_id><sourcerecordid>A459945214</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-9fd7fc8e6e7ee8ec07e55f675577778c368a36b92996c910c20fe42e93bb3a593</originalsourceid><addsrcrecordid>eNqNk1Fv0zAQxyMEYmPwDRBYQkLw0OLEiRO_IFWDbZU6Veo2Xi3HObeu3LjYzgRPfHXcNpsatAeSh0Tn3_399_kuSd6meJySMv2ytp1rhRlvbQtjnFKc4exZcpoyko1ohsnzo_-T5JX3a4wLUlH6MjnJypzhtGSnyZ-Z9R5ZhS6duNfB2a32G6RbdCFcCx5aGN06EAEaNHGi1o3deu3R1KNvHaBg0bWWzoau7gyga2GUdRsRtG09WoDZ50XoKkZtNItE26DF_AbdtbUwopXwOnmhhPHwpv-eJXcX32_Pr0az-eX0fDIbScqyMGKqKZWsgEIJUIHEJRSFomVRlPGpJKGVILRmGWNUshTLDCvIM2CkrokoGDlL3h90t8Z63tfO85RVJSkyUhSRmB6Ixoo13zq9Ee43t0LzfcC6JRcuaGmAQ6WIUHkTHeR5VbNakbqSjaDQ0KYQELW-9rt19QYaCW1wwgxEhyutXvGlvec5K3OMd3Y_9QLO_uzAB77RXoKJNQPbRd9ViqPpipCIfvgHffp0PbUU8QC6VTbuK3eifJIXjOVFluaRGj9BxbeBjZax0ZSO8UHC50FCZAL8CkvRec-nN4v_Z-c_huzHI3YFwoSVt6bbd9YQzA9g7ELvHajHIqeY7-bkoRp8Nye8n5OY9u74gh6THgaD_AU6DQ7_</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1987352355</pqid></control><display><type>article</type><title>Loss of Gravitropism in Farnesene-Treated Arabidopsis Is Due to Microtubule Malformations Related to Hormonal and ROS Unbalance</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><source>Public Library of Science (PLoS)</source><creator>Araniti, Fabrizio ; Graña, Elisa ; Krasuska, Urszula ; Bogatek, Renata ; Reigosa, Manuel J ; Abenavoli, Maria Rosa ; Sánchez-Moreiras, Adela M</creator><contributor>Rahman, Abidur</contributor><creatorcontrib>Araniti, Fabrizio ; Graña, Elisa ; Krasuska, Urszula ; Bogatek, Renata ; Reigosa, Manuel J ; Abenavoli, Maria Rosa ; Sánchez-Moreiras, Adela M ; Rahman, Abidur</creatorcontrib><description>Mode of action of farnesene, a volatile sesquiterpene commonly found in the essential oils of several plants, was deeply studied on the model species Arabidopsis thaliana. The effects of farnesene on the Arabidopsis root morphology were evaluated by different microscopic techniques. As well, microtubules immunolabeling, phytohormone measurements and ROS staining helped us to elucidate the single or multi-modes of action of this sesquiterpene on plant metabolism. Farnesene-treated roots showed a strong growth inhibition and marked modifications on morphology, important tissue alterations, cellular damages and anisotropic growth. Left-handed growth of farnesene-treated roots, reverted by taxol (a known microtubule stabilizer), was related to microtubule condensation and disorganization. As well, the inhibition of primary root growth, lateral root number, lateral root length, and both root hairs length and density could be explained by the strong increment in ethylene production and auxin content detected in farnesene-treated seedlings. Microtubule alteration and hormonal unbalance appear as important components in the mode of action of farnesene and confirm the strong phytotoxic potential of this sesquiterpene.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0160202</identifier><identifier>PMID: 27490179</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Aphidoidea ; Arabidopsis ; Arabidopsis - drug effects ; Arabidopsis - growth & development ; Arabidopsis - metabolism ; Arabidopsis thaliana ; Biology and Life Sciences ; Cell division ; Cellulose ; Condensates ; Essential oils ; Ethylenes - metabolism ; Farnesene ; Gene expression ; Genetic aspects ; Gravitropism ; Handedness ; Herbicides ; Herbivores ; Hydrogen Peroxide - analysis ; Indoleacetic Acids - metabolism ; Inhibition ; Life sciences ; Microscopy, Electron, Transmission ; Microtubules ; Microtubules - metabolism ; Mode of action ; Morphology ; Nitric Oxide - metabolism ; Paclitaxel ; Paclitaxel - pharmacology ; Physical Sciences ; Physiological aspects ; Physiology ; Plant biology ; Plant growth ; Plant Growth Regulators - metabolism ; Plant hormones ; Plant metabolism ; Plant Roots - drug effects ; Plant Roots - growth & development ; Plant Roots - physiology ; Reactive Oxygen Species - metabolism ; Research and Analysis Methods ; Root hairs ; Roots ; Seedlings ; Seedlings - drug effects ; Seedlings - growth & development ; Sesquiterpenes - pharmacology ; Soil sciences ; Superoxides - analysis ; Taxol ; Weeds ; Zea mays</subject><ispartof>PloS one, 2016-08, Vol.11 (8), p.e0160202-e0160202</ispartof><rights>COPYRIGHT 2016 Public Library of Science</rights><rights>2016 Araniti et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2016 Araniti et al 2016 Araniti et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-9fd7fc8e6e7ee8ec07e55f675577778c368a36b92996c910c20fe42e93bb3a593</citedby><cites>FETCH-LOGICAL-c692t-9fd7fc8e6e7ee8ec07e55f675577778c368a36b92996c910c20fe42e93bb3a593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974009/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974009/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79343,79344</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27490179$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Rahman, Abidur</contributor><creatorcontrib>Araniti, Fabrizio</creatorcontrib><creatorcontrib>Graña, Elisa</creatorcontrib><creatorcontrib>Krasuska, Urszula</creatorcontrib><creatorcontrib>Bogatek, Renata</creatorcontrib><creatorcontrib>Reigosa, Manuel J</creatorcontrib><creatorcontrib>Abenavoli, Maria Rosa</creatorcontrib><creatorcontrib>Sánchez-Moreiras, Adela M</creatorcontrib><title>Loss of Gravitropism in Farnesene-Treated Arabidopsis Is Due to Microtubule Malformations Related to Hormonal and ROS Unbalance</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Mode of action of farnesene, a volatile sesquiterpene commonly found in the essential oils of several plants, was deeply studied on the model species Arabidopsis thaliana. The effects of farnesene on the Arabidopsis root morphology were evaluated by different microscopic techniques. As well, microtubules immunolabeling, phytohormone measurements and ROS staining helped us to elucidate the single or multi-modes of action of this sesquiterpene on plant metabolism. Farnesene-treated roots showed a strong growth inhibition and marked modifications on morphology, important tissue alterations, cellular damages and anisotropic growth. Left-handed growth of farnesene-treated roots, reverted by taxol (a known microtubule stabilizer), was related to microtubule condensation and disorganization. As well, the inhibition of primary root growth, lateral root number, lateral root length, and both root hairs length and density could be explained by the strong increment in ethylene production and auxin content detected in farnesene-treated seedlings. Microtubule alteration and hormonal unbalance appear as important components in the mode of action of farnesene and confirm the strong phytotoxic potential of this sesquiterpene.</description><subject>Aphidoidea</subject><subject>Arabidopsis</subject><subject>Arabidopsis - drug effects</subject><subject>Arabidopsis - growth & development</subject><subject>Arabidopsis - metabolism</subject><subject>Arabidopsis thaliana</subject><subject>Biology and Life Sciences</subject><subject>Cell division</subject><subject>Cellulose</subject><subject>Condensates</subject><subject>Essential oils</subject><subject>Ethylenes - metabolism</subject><subject>Farnesene</subject><subject>Gene expression</subject><subject>Genetic aspects</subject><subject>Gravitropism</subject><subject>Handedness</subject><subject>Herbicides</subject><subject>Herbivores</subject><subject>Hydrogen Peroxide - analysis</subject><subject>Indoleacetic Acids - metabolism</subject><subject>Inhibition</subject><subject>Life sciences</subject><subject>Microscopy, Electron, Transmission</subject><subject>Microtubules</subject><subject>Microtubules - metabolism</subject><subject>Mode of action</subject><subject>Morphology</subject><subject>Nitric Oxide - metabolism</subject><subject>Paclitaxel</subject><subject>Paclitaxel - pharmacology</subject><subject>Physical Sciences</subject><subject>Physiological aspects</subject><subject>Physiology</subject><subject>Plant biology</subject><subject>Plant growth</subject><subject>Plant Growth Regulators - metabolism</subject><subject>Plant hormones</subject><subject>Plant metabolism</subject><subject>Plant Roots - drug effects</subject><subject>Plant Roots - growth & development</subject><subject>Plant Roots - physiology</subject><subject>Reactive Oxygen Species - metabolism</subject><subject>Research and Analysis Methods</subject><subject>Root hairs</subject><subject>Roots</subject><subject>Seedlings</subject><subject>Seedlings - drug effects</subject><subject>Seedlings - growth & development</subject><subject>Sesquiterpenes - pharmacology</subject><subject>Soil sciences</subject><subject>Superoxides - analysis</subject><subject>Taxol</subject><subject>Weeds</subject><subject>Zea mays</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNk1Fv0zAQxyMEYmPwDRBYQkLw0OLEiRO_IFWDbZU6Veo2Xi3HObeu3LjYzgRPfHXcNpsatAeSh0Tn3_399_kuSd6meJySMv2ytp1rhRlvbQtjnFKc4exZcpoyko1ohsnzo_-T5JX3a4wLUlH6MjnJypzhtGSnyZ-Z9R5ZhS6duNfB2a32G6RbdCFcCx5aGN06EAEaNHGi1o3deu3R1KNvHaBg0bWWzoau7gyga2GUdRsRtG09WoDZ50XoKkZtNItE26DF_AbdtbUwopXwOnmhhPHwpv-eJXcX32_Pr0az-eX0fDIbScqyMGKqKZWsgEIJUIHEJRSFomVRlPGpJKGVILRmGWNUshTLDCvIM2CkrokoGDlL3h90t8Z63tfO85RVJSkyUhSRmB6Ixoo13zq9Ee43t0LzfcC6JRcuaGmAQ6WIUHkTHeR5VbNakbqSjaDQ0KYQELW-9rt19QYaCW1wwgxEhyutXvGlvec5K3OMd3Y_9QLO_uzAB77RXoKJNQPbRd9ViqPpipCIfvgHffp0PbUU8QC6VTbuK3eifJIXjOVFluaRGj9BxbeBjZax0ZSO8UHC50FCZAL8CkvRec-nN4v_Z-c_huzHI3YFwoSVt6bbd9YQzA9g7ELvHajHIqeY7-bkoRp8Nye8n5OY9u74gh6THgaD_AU6DQ7_</recordid><startdate>20160804</startdate><enddate>20160804</enddate><creator>Araniti, Fabrizio</creator><creator>Graña, Elisa</creator><creator>Krasuska, Urszula</creator><creator>Bogatek, Renata</creator><creator>Reigosa, Manuel J</creator><creator>Abenavoli, Maria Rosa</creator><creator>Sánchez-Moreiras, Adela M</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20160804</creationdate><title>Loss of Gravitropism in Farnesene-Treated Arabidopsis Is Due to Microtubule Malformations Related to Hormonal and ROS Unbalance</title><author>Araniti, Fabrizio ; Graña, Elisa ; Krasuska, Urszula ; Bogatek, Renata ; Reigosa, Manuel J ; Abenavoli, Maria Rosa ; Sánchez-Moreiras, Adela M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-9fd7fc8e6e7ee8ec07e55f675577778c368a36b92996c910c20fe42e93bb3a593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Aphidoidea</topic><topic>Arabidopsis</topic><topic>Arabidopsis - drug effects</topic><topic>Arabidopsis - growth & development</topic><topic>Arabidopsis - metabolism</topic><topic>Arabidopsis thaliana</topic><topic>Biology and Life Sciences</topic><topic>Cell division</topic><topic>Cellulose</topic><topic>Condensates</topic><topic>Essential oils</topic><topic>Ethylenes - metabolism</topic><topic>Farnesene</topic><topic>Gene expression</topic><topic>Genetic aspects</topic><topic>Gravitropism</topic><topic>Handedness</topic><topic>Herbicides</topic><topic>Herbivores</topic><topic>Hydrogen Peroxide - analysis</topic><topic>Indoleacetic Acids - metabolism</topic><topic>Inhibition</topic><topic>Life sciences</topic><topic>Microscopy, Electron, Transmission</topic><topic>Microtubules</topic><topic>Microtubules - metabolism</topic><topic>Mode of action</topic><topic>Morphology</topic><topic>Nitric Oxide - metabolism</topic><topic>Paclitaxel</topic><topic>Paclitaxel - pharmacology</topic><topic>Physical Sciences</topic><topic>Physiological aspects</topic><topic>Physiology</topic><topic>Plant biology</topic><topic>Plant growth</topic><topic>Plant Growth Regulators - metabolism</topic><topic>Plant hormones</topic><topic>Plant metabolism</topic><topic>Plant Roots - drug effects</topic><topic>Plant Roots - growth & development</topic><topic>Plant Roots - physiology</topic><topic>Reactive Oxygen Species - metabolism</topic><topic>Research and Analysis Methods</topic><topic>Root hairs</topic><topic>Roots</topic><topic>Seedlings</topic><topic>Seedlings - drug effects</topic><topic>Seedlings - growth & development</topic><topic>Sesquiterpenes - pharmacology</topic><topic>Soil sciences</topic><topic>Superoxides - analysis</topic><topic>Taxol</topic><topic>Weeds</topic><topic>Zea mays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Araniti, Fabrizio</creatorcontrib><creatorcontrib>Graña, Elisa</creatorcontrib><creatorcontrib>Krasuska, Urszula</creatorcontrib><creatorcontrib>Bogatek, Renata</creatorcontrib><creatorcontrib>Reigosa, Manuel J</creatorcontrib><creatorcontrib>Abenavoli, Maria Rosa</creatorcontrib><creatorcontrib>Sánchez-Moreiras, Adela M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Araniti, Fabrizio</au><au>Graña, Elisa</au><au>Krasuska, Urszula</au><au>Bogatek, Renata</au><au>Reigosa, Manuel J</au><au>Abenavoli, Maria Rosa</au><au>Sánchez-Moreiras, Adela M</au><au>Rahman, Abidur</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Loss of Gravitropism in Farnesene-Treated Arabidopsis Is Due to Microtubule Malformations Related to Hormonal and ROS Unbalance</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2016-08-04</date><risdate>2016</risdate><volume>11</volume><issue>8</issue><spage>e0160202</spage><epage>e0160202</epage><pages>e0160202-e0160202</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Mode of action of farnesene, a volatile sesquiterpene commonly found in the essential oils of several plants, was deeply studied on the model species Arabidopsis thaliana. The effects of farnesene on the Arabidopsis root morphology were evaluated by different microscopic techniques. As well, microtubules immunolabeling, phytohormone measurements and ROS staining helped us to elucidate the single or multi-modes of action of this sesquiterpene on plant metabolism. Farnesene-treated roots showed a strong growth inhibition and marked modifications on morphology, important tissue alterations, cellular damages and anisotropic growth. Left-handed growth of farnesene-treated roots, reverted by taxol (a known microtubule stabilizer), was related to microtubule condensation and disorganization. As well, the inhibition of primary root growth, lateral root number, lateral root length, and both root hairs length and density could be explained by the strong increment in ethylene production and auxin content detected in farnesene-treated seedlings. Microtubule alteration and hormonal unbalance appear as important components in the mode of action of farnesene and confirm the strong phytotoxic potential of this sesquiterpene.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>27490179</pmid><doi>10.1371/journal.pone.0160202</doi><tpages>e0160202</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2016-08, Vol.11 (8), p.e0160202-e0160202 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1987352355 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Aphidoidea Arabidopsis Arabidopsis - drug effects Arabidopsis - growth & development Arabidopsis - metabolism Arabidopsis thaliana Biology and Life Sciences Cell division Cellulose Condensates Essential oils Ethylenes - metabolism Farnesene Gene expression Genetic aspects Gravitropism Handedness Herbicides Herbivores Hydrogen Peroxide - analysis Indoleacetic Acids - metabolism Inhibition Life sciences Microscopy, Electron, Transmission Microtubules Microtubules - metabolism Mode of action Morphology Nitric Oxide - metabolism Paclitaxel Paclitaxel - pharmacology Physical Sciences Physiological aspects Physiology Plant biology Plant growth Plant Growth Regulators - metabolism Plant hormones Plant metabolism Plant Roots - drug effects Plant Roots - growth & development Plant Roots - physiology Reactive Oxygen Species - metabolism Research and Analysis Methods Root hairs Roots Seedlings Seedlings - drug effects Seedlings - growth & development Sesquiterpenes - pharmacology Soil sciences Superoxides - analysis Taxol Weeds Zea mays |
| title | Loss of Gravitropism in Farnesene-Treated Arabidopsis Is Due to Microtubule Malformations Related to Hormonal and ROS Unbalance |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T19%3A13%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Loss%20of%20Gravitropism%20in%20Farnesene-Treated%20Arabidopsis%20Is%20Due%20to%20Microtubule%20Malformations%20Related%20to%20Hormonal%20and%20ROS%20Unbalance&rft.jtitle=PloS%20one&rft.au=Araniti,%20Fabrizio&rft.date=2016-08-04&rft.volume=11&rft.issue=8&rft.spage=e0160202&rft.epage=e0160202&rft.pages=e0160202-e0160202&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0160202&rft_dat=%3Cgale_plos_%3EA459945214%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1987352355&rft_id=info:pmid/27490179&rft_galeid=A459945214&rft_doaj_id=oai_doaj_org_article_e8f3af4d5f6448b9bf3b8cda6ed6d5ae&rfr_iscdi=true |