Simple Elastic Network Models for Exhaustive Analysis of Long Double-Stranded DNA Dynamics with Sequence Geometry Dependence

Simple elastic network models of DNA were developed to reveal the structure-dynamics relationships for several nucleotide sequences. First, we propose a simple all-atom elastic network model of DNA that can explain the profiles of temperature factors for several crystal structures of DNA. Second, we...

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Veröffentlicht in:PloS one 2015-12, Vol.10 (12), p.e0143760-e0143760
Hauptverfasser: Isami, Shuhei, Sakamoto, Naoaki, Nishimori, Hiraku, Awazu, Akinori
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Sprache:eng
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