Overexpression of SMPX in adult skeletal muscle does not change skeletal muscle fiber type or size

Mechanical factors such as stretch are thought to be important in the regulation of muscle phenotype. Small muscle protein X-linked (SMPX) is upregulated by stretch in skeletal muscle and has been suggested to serve both as a transcription factor and a mechanosensor, possibly giving rise to changes...

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Veröffentlicht in:	PloS one 2014-06, Vol.9 (6), p.e99232-e99232
Hauptverfasser:	Eftestøl, Einar, Alver, Tine Norman, Gundersen, Kristian, Bruusgaard, Jo C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bands Biology and Life Sciences Cell Nucleus - metabolism Extracellular matrix Fusion protein Gene expression Genomics Genotype & phenotype HEK293 Cells Humans In vivo methods and tests Insulin-like growth factors Localization Male Mechanical properties Mice Muscle Proteins - genetics Muscle Proteins - metabolism Muscle, Skeletal - cytology Muscle, Skeletal - metabolism Muscles Musculoskeletal system Mutation Myoblasts - metabolism Nuclei Plasmids Protein Transport Protein X Proteins Rats Rats, Wistar Sarcomeres - metabolism Skeletal muscle Transcription factors
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