Ablation of the renal stroma defines its critical role in nephron progenitor and vasculature patterning

The renal stroma is an embryonic cell population located in the cortex that provides a structural framework as well as a source of endothelial progenitors for the developing kidney. The exact role of the renal stroma in normal kidney development hasn't been clearly defined. However, previous st...

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Veröffentlicht in:	PloS one 2014-02, Vol.9 (2), p.e88400-e88400
Hauptverfasser:	Hum, Stephanie, Rymer, Christopher, Schaefer, Caitlin, Bushnell, Daniel, Sims-Lucas, Sunder
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Ablation (Surgery) Analysis Animal models Animals Apoptosis Auditory defects Biology Body Patterning Cell Differentiation Cell division Children & youth Clonal deletion Deformation mechanisms Diphtheria Diphtheria toxin Embryos Epithelium Female Forkhead Transcription Factors - genetics Gene deletion Gene expression Immunofluorescence Kidney - abnormalities Kidney - blood supply Kidney - embryology Kidney - metabolism Kidneys Medicine Mice Morphogenesis Mutants Mutation Nephrology Nephrons - cytology Pattern formation Pediatrics Physicians Physiology Rodents Stem cells Stem Cells - cytology Stromal cells Thermal analysis Thickening Transcription factors Ureter
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