RNA-Seq differential expression analysis: An extended review and a software tool

The correct identification of differentially expressed genes (DEGs) between specific conditions is a key in the understanding phenotypic variation. High-throughput transcriptome sequencing (RNA-Seq) has become the main option for these studies. Thus, the number of methods and softwares for different...

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Veröffentlicht in:	PloS one 2017-12, Vol.12 (12), p.e0190152-e0190152
Hauptverfasser:	Costa-Silva, Juliana, Domingues, Douglas, Lopes, Fabricio Martins
Format:	Artikel
Sprache:	eng
Schlagworte:	Artificial intelligence Binomial distribution Bioinformatics Biology Biology and Life Sciences Biotechnology Computer and Information Sciences Computer programs Computer science Data analysis Data processing Engineering and Technology Experiments Gene Expression Gene mapping Gene sequencing Generalized linear models Genes Genomes Humans Identification methods Mapping Methods Phenotypic variations Production methods Protocol (computers) Research and analysis methods Ribonucleic acid RNA Sequence Analysis, RNA - methods Software Software development tools
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