Generation of insulin-producing cells from the mouse liver using β cell-related gene transfer including Mafa and Mafb

Recent studies on the large Maf transcription factors have shown that Mafb and Mafa have respective and distinctive roles in β-cell development and maturation. However, whether this difference in roles is due to the timing of the gene expression (roughly, expression of Mafb before birth and of Mafa...

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Veröffentlicht in:PloS one 2014-11, Vol.9 (11), p.e113022
Hauptverfasser: Nagasaki, Haruka, Katsumata, Tokio, Oishi, Hisashi, Tai, Pei-Han, Sekiguchi, Yukari, Koshida, Ryusuke, Jung, Yunshin, Kudo, Takashi, Takahashi, Satoru
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