MiRNA expression may account for chronic but not for acute regulation of mRNA expression in human thyroid tumor models

For thyroid tumorigenesis, two main human in vitro models are available: primary cultures of human thyrocytes treated with TSH or EGF/serum as models for autonomous adenomas (AA) or papillary thyroid carcinomas (PTC) respectively, and human thyroid tumor derived cell lines. Previous works of our gro...

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Veröffentlicht in:	PloS one 2014-11, Vol.9 (11), p.e111581-e111581
Hauptverfasser:	Floor, Sébastien L, Hebrant, Aline, Pita, Jaime M, Saiselet, Manuel, Trésallet, Christophe, Libert, Frederick, Andry, Guy, Dumont, Jacques E, van Staveren, Wilma C, Maenhaut, Carine
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biochemistry, Molecular Biology Biology and Life Sciences Biotechnology Cancer Carcinoma, Papillary - genetics Carcinoma, Papillary - metabolism Carcinoma, Papillary - pathology Cell growth Cell Line, Tumor Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - pathology Cells (Biology) DNA microarrays Epidermal Growth Factor - pharmacology Gene expression Gene Expression Regulation, Neoplastic - drug effects Genomics Genotype & phenotype Humans Interdisciplinary aspects Life Sciences Medicine and Health Sciences Messenger RNA MicroRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA Oligonucleotide Array Sequence Analysis Papillary thyroid carcinoma Regulations Ribonucleic acid RNA RNA, Messenger - genetics RNA, Messenger - metabolism Signal transduction Thyrocytes Thyroid Thyroid cancer Thyroid Gland - drug effects Thyroid Gland - metabolism Thyroid Gland - pathology Thyroid Neoplasms - genetics Thyroid Neoplasms - metabolism Thyroid Neoplasms - pathology Thyroid-stimulating hormone Thyrotropin - pharmacology Tissues Tumor cell lines Tumorigenesis Tumors
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