Inflammasome activation is critical to the protective immune response during chemically induced squamous cell carcinoma

Chronic inflammation affects most stages of tumorigenesis, including initiation, promotion, malignant differentiation, invasion and metastasis. Inflammasomes have been described as involved with persistent inflammation and are known to exert both pro and antitumour effects. We evaluated the influenc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2014-09, Vol.9 (9), p.e107170
Hauptverfasser:	Gasparoto, Thais Helena, de Oliveira, Carine Ervolino, de Freitas, Luisa Thomazini, Pinheiro, Claudia Ramos, Hori, Juliana Issa, Garlet, Gustavo Pompermaier, Cavassani, Karen Angélica, Schillaci, Roxana, da Silva, João Santana, Zamboni, Dario Simões, Campanelli, Ana Paula
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene Activation Animals Antitumor activity Apoptosis Biology Biology and Life Sciences Cancer Carcinoma, Squamous Cell - chemically induced Carcinoma, Squamous Cell - immunology Caspase CD25 antigen CD4 antigen CD45RB antigen CD8 antigen Cytokines Dentistry Elastase Female Foxp3 protein Immune response Immune system Immunology Inflammasomes Inflammasomes - physiology Inflammation Interferon Interleukin 18 Lesions Leukocytes (neutrophilic) Lymph nodes Lymph Nodes - immunology Lymphocytes Lymphocytes T Macrophages Medical schools Medicine and Health Sciences Metastases Mice Mice, Inbred C57BL Mice, Knockout Natural killer cells Papilloma Papilloma - chemically induced Papilloma - immunology Peroxidase Proteins Recruitment Skin Neoplasms - immunology Squamous cell carcinoma T cell receptors Tumor necrosis factor-α Tumorigenesis Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!