Nucleases as a barrier to gene silencing in the cotton boll weevil, Anthonomus grandis

RNA interference (RNAi) approaches have been applied as a biotechnological tool for controlling plant insect pests via selective gene down regulation. However, the inefficiency of RNAi mechanism in insects is associated with several barriers, including dsRNA delivery and uptake by the cell, dsRNA in...

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Veröffentlicht in:	PloS one 2017-12, Vol.12 (12), p.e0189600-e0189600
Hauptverfasser:	Almeida Garcia, Rayssa, Lima Pepino Macedo, Leonardo, Cabral do Nascimento, Danila, Gillet, François-Xavier, Moreira-Pinto, Clidia Eduarda, Faheem, Muhammad, Moreschi Basso, Angelina Maria, Mattar Silva, Maria Cristina, Grossi-de-Sa, Maria Fatima
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animal behavior Anthonomus grandis Archives & records Biochemistry Biology and life sciences Biotechnology Boll weevil Chitin Chitin synthase Coleoptera Cotton Deoxyribonucleic acid DNA DNA binding proteins Double-stranded RNA Endonuclease Enzymes Feeding Feeding trials Gene expression Gene silencing Genetic aspects Hypothenemus hampei Insect pests Insects Medicine and Health Sciences Midgut Molecular biology Nuclease Nucleases Pests Phylogeny Physiological aspects Physiology Proteins Research and Analysis Methods Ribonucleic acid RNA RNA-mediated interference
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