aCNViewer: Comprehensive genome-wide visualization of absolute copy number and copy neutral variations

Copy number variations (CNV) include net gains or losses of part or whole chromosomal regions. They differ from copy neutral loss of heterozygosity (cn-LOH) events which do not induce any net change in the copy number and are often associated with uniparental disomy. These phenomena have long been r...

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Veröffentlicht in:	PloS one 2017-12, Vol.12 (12), p.e0189334-e0189334
Hauptverfasser:	Renault, Victor, Tost, Jörg, Pichon, Fabien, Wang-Renault, Shu-Fang, Letouzé, Eric, Imbeaud, Sandrine, Zucman-Rossi, Jessica, Deleuze, Jean-François, How-Kit, Alexandre
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Algorithms Biochemistry, Molecular Biology Bioinformatics Biology and Life Sciences Cancer Chromosomes Computer and Information Sciences Copy number Copy number variations Deoxyribonucleic acid DNA Epigenetics Gene expression Genetics Genome-wide association studies Genomes Genomics Graphical representations Hepatocellular carcinoma Heterozygosity Histograms Identification Laboratories Life Sciences Liver cancer Loss of heterozygosity Medicine and Health Sciences Physical Sciences Research and analysis methods Single-nucleotide polymorphism Tumor suppressor genes Tumors Uniparental disomy Visualization
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