A favorable cardiometabolic profile is associated with the G allele of the genetic variant rs5068 in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA)

In whites, the minor G allele of the atrial natriuretic peptide (ANP) genetic variant rs5068 is associated with higher circulating levels of ANP and B-type natriuretic peptide (BNP), lower risk of hypertension, higher high-density lipoprotein (HDL) cholesterol plasma levels, and lower prevalence of...

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Veröffentlicht in:	PloS one 2017-12, Vol.12 (12), p.e0189858-e0189858
Hauptverfasser:	Cannone, Valentina, Scott, Christopher G, Decker, Paul A, Larson, Nicholas B, Palmas, Walter, Taylor, Kent D, Wang, Thomas J, Gupta, Deepak K, Bielinski, Suzette J, Burnett, Jr, John C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adjustment African Americans Age Aged Aged, 80 and over Alleles Arteriosclerosis Atherosclerosis Atherosclerosis - ethnology Atherosclerosis - genetics Atrial Natriuretic Factor - genetics Atrial natriuretic peptide Biology and Life Sciences Blood pressure Body mass Body mass index Brain natriuretic peptide Cardiovascular Diseases - ethnology Cardiovascular Diseases - genetics Cardiovascular Diseases - prevention & control Cardiovascular System Cholesterol Cholesterol, HDL - blood Cohort Studies Diabetes Diabetes mellitus Ethnic Groups Female Genetic aspects Genetic diversity Genetic variance Genotype Genotypes Geography Health aspects Health risk assessment Health sciences High density lipoprotein Humans Hypertension Insulin Insulin - blood Insulin resistance Laboratories Male Medicine Medicine and Health Sciences Metabolic syndrome Metabolic Syndrome - blood Metabolic syndrome X Middle Aged Minority & ethnic groups Musculoskeletal system Natriuretic Peptide, Brain - blood Obesity Obesity - blood Obesity - genetics People and places Peptides Phenotype Plasma levels Prevalence Risk factors Rodents Sex Triglycerides Triglycerides - blood United States
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