Newly established monoclonal antibody diagnostic assays for Schistosoma mansoni direct detection in areas of low endemicity

Current available methods for diagnosis of schistosomiasis mansoni lack sufficient sensitivity, which results in underreporting of infectious in areas of low endemicity. We developed three novel diagnostic methodologies for the direct detection of schistosome infection in serum samples. These three...

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Veröffentlicht in:	PloS one 2014-01, Vol.9 (1), p.e87777-e87777
Hauptverfasser:	Grenfell, Rafaella Fortini Queiroz, Coelho, Paulo Marcos Zech, Taboada, Diana, de Mattos, Ana Carolina Alves, Davis, Ruth, Harn, Donald A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Animals Antibodies, Helminth - chemistry Antibodies, Helminth - immunology Antibodies, Monoclonal - chemistry Antibodies, Monoclonal - immunology Antigenic determinants Antigens Antigens, Helminth - blood Antigens, Helminth - immunology Assaying Biology Carbohydrates Diagnostic systems Dilution Eggs Enzyme-linked immunosorbent assay Epitopes Ethics Female Fluorescence Glycoproteins - blood Glycoproteins - immunology Granulocytes Health aspects Helminth Proteins - blood Helminth Proteins - immunology Humans Immunomagnetic separation Infections Infectious diseases International organizations Laboratories Male Medical diagnosis Medicine Microscopy Middle Aged Monoclonal antibodies Parasites Parasitic diseases Patients Population Qualitative analysis Schistosoma Schistosoma mansoni Schistosomiasis Schistosomiasis mansoni - blood Schistosomiasis mansoni - immunology Sensitivity Sensitivity analysis Separation Tropical diseases Urine Veterinary colleges Veterinary medicine
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