Functional cortical hubs in the eyes-closed resting human brain from an electrophysiological perspective using magnetoencephalography
It is not clear whether specific brain areas act as hubs in the eyes-closed (EC) resting state, which is an unconstrained state free from any passive or active tasks. Here, we used electrophysiological magnetoencephalography (MEG) signals to study functional cortical hubs in 88 participants. We iden...
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| Veröffentlicht in: | PloS one 2013-07, Vol.8 (7), p.e68192-e68192 |
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| creator | Jin, Seung-Hyun Jeong, Woorim Seol, Jaeho Kwon, Jiyeon Chung, Chun Kee |
| description | It is not clear whether specific brain areas act as hubs in the eyes-closed (EC) resting state, which is an unconstrained state free from any passive or active tasks. Here, we used electrophysiological magnetoencephalography (MEG) signals to study functional cortical hubs in 88 participants. We identified several multispectral cortical hubs. Although cortical hubs vary slightly with different applied measures and frequency bands, the most consistent hubs were observed in the medial and posterior cingulate cortex, the left dorsolateral superior frontal cortex, and the left pole of the middle temporal cortex. Hubs were characterized as connector nodes integrating EC resting state functional networks. Hubs in the gamma band were more likely to include midline structures. Our results confirm the existence of multispectral cortical cores in EC resting state functional networks based on MEG and imply the existence of optimized functional networks in the resting brain. |
| doi_str_mv | 10.1371/journal.pone.0068192 |
| format | Article |
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Our results confirm the existence of multispectral cortical cores in EC resting state functional networks based on MEG and imply the existence of optimized functional networks in the resting brain.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0068192</identifier><identifier>PMID: 23874535</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adolescent ; Adult ; Biology ; Brain ; Brain research ; Brain Waves ; Cerebral Cortex - physiology ; Cores ; Cortex (cingulate) ; Cortex (frontal) ; Cortex (temporal) ; Electrophysiological Phenomena ; Female ; Frequencies ; Hubs ; Humans ; Hypotheses ; Magnetoencephalography ; Male ; Medical research ; Medicine ; Networks ; Neurosciences ; Neurosurgery ; Rest ; Studies ; Young Adult</subject><ispartof>PloS one, 2013-07, Vol.8 (7), p.e68192-e68192</ispartof><rights>COPYRIGHT 2013 Public Library of Science</rights><rights>2013 Jin et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 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Here, we used electrophysiological magnetoencephalography (MEG) signals to study functional cortical hubs in 88 participants. We identified several multispectral cortical hubs. Although cortical hubs vary slightly with different applied measures and frequency bands, the most consistent hubs were observed in the medial and posterior cingulate cortex, the left dorsolateral superior frontal cortex, and the left pole of the middle temporal cortex. Hubs were characterized as connector nodes integrating EC resting state functional networks. Hubs in the gamma band were more likely to include midline structures. 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| subjects | Adolescent Adult Biology Brain Brain research Brain Waves Cerebral Cortex - physiology Cores Cortex (cingulate) Cortex (frontal) Cortex (temporal) Electrophysiological Phenomena Female Frequencies Hubs Humans Hypotheses Magnetoencephalography Male Medical research Medicine Networks Neurosciences Neurosurgery Rest Studies Young Adult |
| title | Functional cortical hubs in the eyes-closed resting human brain from an electrophysiological perspective using magnetoencephalography |
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