Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1

Members of the Plasmodium falciparum Erythrocyte Membrane protein 1 (PfEMP1) family expressed on the surface of malaria-infected erythrocytes mediate binding of the parasite to different receptors on the vascular lining. This process drives pathologies, and severe childhood malaria has been associat...

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Veröffentlicht in:	PloS one 2013-07, Vol.8 (7), p.e69117-e69117
Hauptverfasser:	Berger, Sanne S, Turner, Louise, Wang, Christian W, Petersen, Jens E V, Kraft, Maria, Lusingu, John P A, Mmbando, Bruno, Marquard, Andrea M, Bengtsson, Dominique B A C, Hviid, Lars, Nielsen, Morten A, Theander, Thor G, Lavstsen, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Protozoan - immunology Antibodies, Protozoan - metabolism Antigens, Protozoan - chemistry Antigens, Protozoan - genetics Antigens, Protozoan - immunology Antigens, Protozoan - metabolism Binding Bone marrow Bone Marrow Cells - metabolism Cassettes Cell adhesion & migration Children Chondroitin sulfate Cluster Analysis Conserved Sequence Development and progression Endothelial cells Endothelial Cells - metabolism Erythrocyte membrane protein 1 Erythrocytes Erythrocytes - metabolism Erythrocytes - parasitology Gene Expression Regulation Genes Hemoglobin Hemoglobins Hospitals Humans Immunoglobulin G - immunology Immunoglobulin G - metabolism Immunoglobulins Immunology Infectious diseases Malaria Malaria, Falciparum - immunology Malaria, Falciparum - metabolism Malaria, Falciparum - prevention & control Medical research Membrane proteins Mortality Parasites Parasitology Pediatric diseases Plasmodium falciparum Plasmodium falciparum - genetics Plasmodium falciparum - immunology Plasmodium falciparum - metabolism Platelet Endothelial Cell Adhesion Molecule-1 - metabolism Protein Binding Protein Interaction Domains and Motifs Proteins Protozoan Proteins - chemistry Protozoan Proteins - genetics Protozoan Proteins - metabolism Receptors Studies Transcriptome Vector-borne diseases Womens health
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