Morphological study of the eye and adnexa in capuchin monkeys (Sapajus sp.)
The objective of this study was to describe the anatomic and histologic features of the Sapajus sp. eye, comparing similarities and differences of humans and other species of non-human primates for biomedical research purposes. Computed tomography (CT) of adnexa, eye and orbit live animal, as well a...
Gespeichert in:
| Veröffentlicht in: | PloS one 2017-12, Vol.12 (12), p.e0186569-e0186569 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0186569 |
|---|---|
| container_issue | 12 |
| container_start_page | e0186569 |
| container_title | PloS one |
| container_volume | 12 |
| creator | Silva, Danielle Nascimento Oriá, Arianne Pontes Araujo, Nayone Lantyer Martins-Filho, Emanoel Muramoto, Caterina Libório, Fernanda de Azevedo Estrela-Lima, Alessandra |
| description | The objective of this study was to describe the anatomic and histologic features of the Sapajus sp. eye, comparing similarities and differences of humans and other species of non-human primates for biomedical research purposes. Computed tomography (CT) of adnexa, eye and orbit live animal, as well as formolized pieces of the same structures of Sapajus sp. for anatomical and histological study were also performed. The anatomical description of the eye and adnexa was performed using the techniques of topographic dissection and exenteration. Histological fragments were fixated in buffered formalin 10%, processed by the routine paraffin inclusion technique, stained with hematoxylin-eosin and special stains. CT scan evaluation showed no differences between the live animal and the formolized head on identification of visual apparatus structures. Anatomic and histologic evaluation revealed rounded orbit, absence of the supraorbital foramen and frontal notch, little exposure of the sclera, with slight pigmentation of the exposed area and marked pigmentation at the sclerocorneal junction. Masson's Trichrome revealed the Meibomian glands, the corneal epithelium and Bowman's membrane; in the choroid, melanocytes and Bruch's membrane were observed; and in the retina, cones and rods as well as, optic nerve, the lamina cribrosa of the nerve fibers bundles. Toluidine blue highlighted the membranes: Bowman, Descemet and the endothelium; in the choroid: melanocytes; and in the retina: nuclear layers and retinal pigment epithelium. In view of the observed results Sapajus sp. is an important experimental model for research in the ophthalmology field, which has been shown due to the high similarity of its anatomical and histological structures with the human species. |
| doi_str_mv | 10.1371/journal.pone.0186569 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1973027175</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A517544024</galeid><doaj_id>oai_doaj_org_article_082bb0344c3e48e686f1d2edd5a5b591</doaj_id><sourcerecordid>A517544024</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-540c740f851694f30c96beec117596461435c4d3197307ee52ffabfc9e69ae9c3</originalsourceid><addsrcrecordid>eNqNkk1v1DAQhiMEoqXwDxBEQkLtYRd_J74gVRUfK4oqUeBqOc5k4yVrhzhB3X-P002rDeoB-WBr_Mw7nvGbJC8xWmKa4XcbP3RON8vWO1ginAsu5KPkGEtKFoIg-vjgfJQ8C2GDEKe5EE-TIyIJEnlOjpMvX33X1r7xa2t0k4Z-KHepr9K-hhR2kGpXprp0cKNT61Kj28HU8bD17hfsQnp6rVu9GUIa2uXZ8-RJpZsAL6b9JPnx8cP3i8-Ly6tPq4vzy4URkvQLzpDJGKpyjoVkFUVGigLAYJxxKZjAjHLDSoplRlEGwElV6aIyEoTUIA09SV7vddvGBzXNIahbnmRRJRKrPVF6vVFtZ7e62ymvrboN-G6tdNdb04BCOSkKRBkzFFgOIhcVLgmUJde84BJHrfdTtaHYQmnA9Z1uZqLzG2drtfZ_FM-w4JJFgdNJoPO_Bwi92tpgoGm0Az_s3804lXxE3_yDPtzdRK11bMC6yse6ZhRV5zwCjCEyai0foOIqYWtNNE1lY3yWcDZLiEwPN_1aDyGo1fW3_2evfs7ZtwdsDbrp6-CbobfehTnI9qDpfAgdVPdDxkiNnr-bhho9rybPx7RXhx90n3RncvoXuC757Q</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1973027175</pqid></control><display><type>article</type><title>Morphological study of the eye and adnexa in capuchin monkeys (Sapajus sp.)</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><source>Public Library of Science (PLoS)</source><creator>Silva, Danielle Nascimento ; Oriá, Arianne Pontes ; Araujo, Nayone Lantyer ; Martins-Filho, Emanoel ; Muramoto, Caterina ; Libório, Fernanda de Azevedo ; Estrela-Lima, Alessandra</creator><creatorcontrib>Silva, Danielle Nascimento ; Oriá, Arianne Pontes ; Araujo, Nayone Lantyer ; Martins-Filho, Emanoel ; Muramoto, Caterina ; Libório, Fernanda de Azevedo ; Estrela-Lima, Alessandra</creatorcontrib><description>The objective of this study was to describe the anatomic and histologic features of the Sapajus sp. eye, comparing similarities and differences of humans and other species of non-human primates for biomedical research purposes. Computed tomography (CT) of adnexa, eye and orbit live animal, as well as formolized pieces of the same structures of Sapajus sp. for anatomical and histological study were also performed. The anatomical description of the eye and adnexa was performed using the techniques of topographic dissection and exenteration. Histological fragments were fixated in buffered formalin 10%, processed by the routine paraffin inclusion technique, stained with hematoxylin-eosin and special stains. CT scan evaluation showed no differences between the live animal and the formolized head on identification of visual apparatus structures. Anatomic and histologic evaluation revealed rounded orbit, absence of the supraorbital foramen and frontal notch, little exposure of the sclera, with slight pigmentation of the exposed area and marked pigmentation at the sclerocorneal junction. Masson's Trichrome revealed the Meibomian glands, the corneal epithelium and Bowman's membrane; in the choroid, melanocytes and Bruch's membrane were observed; and in the retina, cones and rods as well as, optic nerve, the lamina cribrosa of the nerve fibers bundles. Toluidine blue highlighted the membranes: Bowman, Descemet and the endothelium; in the choroid: melanocytes; and in the retina: nuclear layers and retinal pigment epithelium. In view of the observed results Sapajus sp. is an important experimental model for research in the ophthalmology field, which has been shown due to the high similarity of its anatomical and histological structures with the human species.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0186569</identifier><identifier>PMID: 29206882</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Animal sciences ; Animals ; Biology and Life Sciences ; Biomedical research ; CAT scans ; Cebinae ; Cebus ; Computed tomography ; Cones ; Cornea ; Dissection ; Endothelium ; Epithelium ; Evaluation ; Eye ; Eye - anatomy & histology ; Eye - diagnostic imaging ; Fruits ; Glands ; Male ; Medicine and Health Sciences ; Melanocytes ; Membranes ; Monkeys ; Monkeys & apes ; Morphology (Biology) ; Oculomotor Muscles - anatomy & histology ; Oculomotor Muscles - diagnostic imaging ; Ophthalmology ; Optic nerve ; Optical fibers ; Paraffin ; Pathology ; Pigmentation ; Primates ; Retina ; Retinal pigment epithelium ; Rods ; Studies ; Toluidine ; Toluidine blue ; Tomography ; Tomography, X-Ray Computed ; Veterinary medicine ; Veterinary services ; Zoology</subject><ispartof>PloS one, 2017-12, Vol.12 (12), p.e0186569-e0186569</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Silva et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2017 Silva et al 2017 Silva et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-540c740f851694f30c96beec117596461435c4d3197307ee52ffabfc9e69ae9c3</citedby><cites>FETCH-LOGICAL-c692t-540c740f851694f30c96beec117596461435c4d3197307ee52ffabfc9e69ae9c3</cites><orcidid>0000-0002-9879-7999</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716594/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716594/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79342,79343</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29206882$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Silva, Danielle Nascimento</creatorcontrib><creatorcontrib>Oriá, Arianne Pontes</creatorcontrib><creatorcontrib>Araujo, Nayone Lantyer</creatorcontrib><creatorcontrib>Martins-Filho, Emanoel</creatorcontrib><creatorcontrib>Muramoto, Caterina</creatorcontrib><creatorcontrib>Libório, Fernanda de Azevedo</creatorcontrib><creatorcontrib>Estrela-Lima, Alessandra</creatorcontrib><title>Morphological study of the eye and adnexa in capuchin monkeys (Sapajus sp.)</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>The objective of this study was to describe the anatomic and histologic features of the Sapajus sp. eye, comparing similarities and differences of humans and other species of non-human primates for biomedical research purposes. Computed tomography (CT) of adnexa, eye and orbit live animal, as well as formolized pieces of the same structures of Sapajus sp. for anatomical and histological study were also performed. The anatomical description of the eye and adnexa was performed using the techniques of topographic dissection and exenteration. Histological fragments were fixated in buffered formalin 10%, processed by the routine paraffin inclusion technique, stained with hematoxylin-eosin and special stains. CT scan evaluation showed no differences between the live animal and the formolized head on identification of visual apparatus structures. Anatomic and histologic evaluation revealed rounded orbit, absence of the supraorbital foramen and frontal notch, little exposure of the sclera, with slight pigmentation of the exposed area and marked pigmentation at the sclerocorneal junction. Masson's Trichrome revealed the Meibomian glands, the corneal epithelium and Bowman's membrane; in the choroid, melanocytes and Bruch's membrane were observed; and in the retina, cones and rods as well as, optic nerve, the lamina cribrosa of the nerve fibers bundles. Toluidine blue highlighted the membranes: Bowman, Descemet and the endothelium; in the choroid: melanocytes; and in the retina: nuclear layers and retinal pigment epithelium. In view of the observed results Sapajus sp. is an important experimental model for research in the ophthalmology field, which has been shown due to the high similarity of its anatomical and histological structures with the human species.</description><subject>Animal sciences</subject><subject>Animals</subject><subject>Biology and Life Sciences</subject><subject>Biomedical research</subject><subject>CAT scans</subject><subject>Cebinae</subject><subject>Cebus</subject><subject>Computed tomography</subject><subject>Cones</subject><subject>Cornea</subject><subject>Dissection</subject><subject>Endothelium</subject><subject>Epithelium</subject><subject>Evaluation</subject><subject>Eye</subject><subject>Eye - anatomy & histology</subject><subject>Eye - diagnostic imaging</subject><subject>Fruits</subject><subject>Glands</subject><subject>Male</subject><subject>Medicine and Health Sciences</subject><subject>Melanocytes</subject><subject>Membranes</subject><subject>Monkeys</subject><subject>Monkeys & apes</subject><subject>Morphology (Biology)</subject><subject>Oculomotor Muscles - anatomy & histology</subject><subject>Oculomotor Muscles - diagnostic imaging</subject><subject>Ophthalmology</subject><subject>Optic nerve</subject><subject>Optical fibers</subject><subject>Paraffin</subject><subject>Pathology</subject><subject>Pigmentation</subject><subject>Primates</subject><subject>Retina</subject><subject>Retinal pigment epithelium</subject><subject>Rods</subject><subject>Studies</subject><subject>Toluidine</subject><subject>Toluidine blue</subject><subject>Tomography</subject><subject>Tomography, X-Ray Computed</subject><subject>Veterinary medicine</subject><subject>Veterinary services</subject><subject>Zoology</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNkk1v1DAQhiMEoqXwDxBEQkLtYRd_J74gVRUfK4oqUeBqOc5k4yVrhzhB3X-P002rDeoB-WBr_Mw7nvGbJC8xWmKa4XcbP3RON8vWO1ginAsu5KPkGEtKFoIg-vjgfJQ8C2GDEKe5EE-TIyIJEnlOjpMvX33X1r7xa2t0k4Z-KHepr9K-hhR2kGpXprp0cKNT61Kj28HU8bD17hfsQnp6rVu9GUIa2uXZ8-RJpZsAL6b9JPnx8cP3i8-Ly6tPq4vzy4URkvQLzpDJGKpyjoVkFUVGigLAYJxxKZjAjHLDSoplRlEGwElV6aIyEoTUIA09SV7vddvGBzXNIahbnmRRJRKrPVF6vVFtZ7e62ymvrboN-G6tdNdb04BCOSkKRBkzFFgOIhcVLgmUJde84BJHrfdTtaHYQmnA9Z1uZqLzG2drtfZ_FM-w4JJFgdNJoPO_Bwi92tpgoGm0Az_s3804lXxE3_yDPtzdRK11bMC6yse6ZhRV5zwCjCEyai0foOIqYWtNNE1lY3yWcDZLiEwPN_1aDyGo1fW3_2evfs7ZtwdsDbrp6-CbobfehTnI9qDpfAgdVPdDxkiNnr-bhho9rybPx7RXhx90n3RncvoXuC757Q</recordid><startdate>20171205</startdate><enddate>20171205</enddate><creator>Silva, Danielle Nascimento</creator><creator>Oriá, Arianne Pontes</creator><creator>Araujo, Nayone Lantyer</creator><creator>Martins-Filho, Emanoel</creator><creator>Muramoto, Caterina</creator><creator>Libório, Fernanda de Azevedo</creator><creator>Estrela-Lima, Alessandra</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-9879-7999</orcidid></search><sort><creationdate>20171205</creationdate><title>Morphological study of the eye and adnexa in capuchin monkeys (Sapajus sp.)</title><author>Silva, Danielle Nascimento ; Oriá, Arianne Pontes ; Araujo, Nayone Lantyer ; Martins-Filho, Emanoel ; Muramoto, Caterina ; Libório, Fernanda de Azevedo ; Estrela-Lima, Alessandra</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-540c740f851694f30c96beec117596461435c4d3197307ee52ffabfc9e69ae9c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animal sciences</topic><topic>Animals</topic><topic>Biology and Life Sciences</topic><topic>Biomedical research</topic><topic>CAT scans</topic><topic>Cebinae</topic><topic>Cebus</topic><topic>Computed tomography</topic><topic>Cones</topic><topic>Cornea</topic><topic>Dissection</topic><topic>Endothelium</topic><topic>Epithelium</topic><topic>Evaluation</topic><topic>Eye</topic><topic>Eye - anatomy & histology</topic><topic>Eye - diagnostic imaging</topic><topic>Fruits</topic><topic>Glands</topic><topic>Male</topic><topic>Medicine and Health Sciences</topic><topic>Melanocytes</topic><topic>Membranes</topic><topic>Monkeys</topic><topic>Monkeys & apes</topic><topic>Morphology (Biology)</topic><topic>Oculomotor Muscles - anatomy & histology</topic><topic>Oculomotor Muscles - diagnostic imaging</topic><topic>Ophthalmology</topic><topic>Optic nerve</topic><topic>Optical fibers</topic><topic>Paraffin</topic><topic>Pathology</topic><topic>Pigmentation</topic><topic>Primates</topic><topic>Retina</topic><topic>Retinal pigment epithelium</topic><topic>Rods</topic><topic>Studies</topic><topic>Toluidine</topic><topic>Toluidine blue</topic><topic>Tomography</topic><topic>Tomography, X-Ray Computed</topic><topic>Veterinary medicine</topic><topic>Veterinary services</topic><topic>Zoology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Silva, Danielle Nascimento</creatorcontrib><creatorcontrib>Oriá, Arianne Pontes</creatorcontrib><creatorcontrib>Araujo, Nayone Lantyer</creatorcontrib><creatorcontrib>Martins-Filho, Emanoel</creatorcontrib><creatorcontrib>Muramoto, Caterina</creatorcontrib><creatorcontrib>Libório, Fernanda de Azevedo</creatorcontrib><creatorcontrib>Estrela-Lima, Alessandra</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Silva, Danielle Nascimento</au><au>Oriá, Arianne Pontes</au><au>Araujo, Nayone Lantyer</au><au>Martins-Filho, Emanoel</au><au>Muramoto, Caterina</au><au>Libório, Fernanda de Azevedo</au><au>Estrela-Lima, Alessandra</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Morphological study of the eye and adnexa in capuchin monkeys (Sapajus sp.)</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2017-12-05</date><risdate>2017</risdate><volume>12</volume><issue>12</issue><spage>e0186569</spage><epage>e0186569</epage><pages>e0186569-e0186569</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>The objective of this study was to describe the anatomic and histologic features of the Sapajus sp. eye, comparing similarities and differences of humans and other species of non-human primates for biomedical research purposes. Computed tomography (CT) of adnexa, eye and orbit live animal, as well as formolized pieces of the same structures of Sapajus sp. for anatomical and histological study were also performed. The anatomical description of the eye and adnexa was performed using the techniques of topographic dissection and exenteration. Histological fragments were fixated in buffered formalin 10%, processed by the routine paraffin inclusion technique, stained with hematoxylin-eosin and special stains. CT scan evaluation showed no differences between the live animal and the formolized head on identification of visual apparatus structures. Anatomic and histologic evaluation revealed rounded orbit, absence of the supraorbital foramen and frontal notch, little exposure of the sclera, with slight pigmentation of the exposed area and marked pigmentation at the sclerocorneal junction. Masson's Trichrome revealed the Meibomian glands, the corneal epithelium and Bowman's membrane; in the choroid, melanocytes and Bruch's membrane were observed; and in the retina, cones and rods as well as, optic nerve, the lamina cribrosa of the nerve fibers bundles. Toluidine blue highlighted the membranes: Bowman, Descemet and the endothelium; in the choroid: melanocytes; and in the retina: nuclear layers and retinal pigment epithelium. In view of the observed results Sapajus sp. is an important experimental model for research in the ophthalmology field, which has been shown due to the high similarity of its anatomical and histological structures with the human species.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>29206882</pmid><doi>10.1371/journal.pone.0186569</doi><tpages>e0186569</tpages><orcidid>https://orcid.org/0000-0002-9879-7999</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2017-12, Vol.12 (12), p.e0186569-e0186569 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1973027175 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Animal sciences Animals Biology and Life Sciences Biomedical research CAT scans Cebinae Cebus Computed tomography Cones Cornea Dissection Endothelium Epithelium Evaluation Eye Eye - anatomy & histology Eye - diagnostic imaging Fruits Glands Male Medicine and Health Sciences Melanocytes Membranes Monkeys Monkeys & apes Morphology (Biology) Oculomotor Muscles - anatomy & histology Oculomotor Muscles - diagnostic imaging Ophthalmology Optic nerve Optical fibers Paraffin Pathology Pigmentation Primates Retina Retinal pigment epithelium Rods Studies Toluidine Toluidine blue Tomography Tomography, X-Ray Computed Veterinary medicine Veterinary services Zoology |
| title | Morphological study of the eye and adnexa in capuchin monkeys (Sapajus sp.) |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T15%3A50%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Morphological%20study%20of%20the%20eye%20and%20adnexa%20in%20capuchin%20monkeys%20(Sapajus%20sp.)&rft.jtitle=PloS%20one&rft.au=Silva,%20Danielle%20Nascimento&rft.date=2017-12-05&rft.volume=12&rft.issue=12&rft.spage=e0186569&rft.epage=e0186569&rft.pages=e0186569-e0186569&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0186569&rft_dat=%3Cgale_plos_%3EA517544024%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1973027175&rft_id=info:pmid/29206882&rft_galeid=A517544024&rft_doaj_id=oai_doaj_org_article_082bb0344c3e48e686f1d2edd5a5b591&rfr_iscdi=true |