Structural basis for the substrate selectivity of Helicobacter pylori NucT nuclease activity

The Phospholipase D (PLD) superfamily of proteins includes a group of enzymes with nuclease activity on various nucleic acid substrates. Here, with the aim of better understanding the substrate specificity determinants in this subfamily, we have characterised the enzymatic activity and the crystal s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2017-12, Vol.12 (12), p.e0189049-e0189049
Hauptverfasser:	Celma, Louisa, Corbinais, Christopher, Vercruyssen, Julien, Veaute, Xavier, de la Sierra-Gallay, Inès Li, Guérois, Raphaël, Busso, Didier, Mathieu, Aurélie, Marsin, Stéphanie, Quevillon-Cheruel, Sophie, Radicella, J Pablo
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Bioinformatics Biology Biology and life sciences Catalysis Catalytic activity Crystal structure Deoxyribonucleic acid DNA Drug resistance Endonuclease Enzymatic activity Enzymes Helicobacter pylori Homology Life Sciences Medicine and Health Sciences Nuclease Nucleic acids Phospholipase Phospholipase D Phospholipases Physical sciences Proteins Salvage Selectivity Signal transduction Substrate specificity Substrates Transformation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!