BRITER: a BMP responsive osteoblast reporter cell line

BMP signaling pathway is critical for vertebrate development and tissue homeostasis. High-throughput molecular genetic screening may reveal novel players regulating BMP signaling response while chemical genetic screening of BMP signaling modifiers may have clinical significance. It is therefore impo...

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Veröffentlicht in:	PloS one 2012-05, Vol.7 (5), p.e37134-e37134
Hauptverfasser:	Yadav, Prem Swaroop, Prashar, Paritosh, Bandyopadhyay, Amitabha
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatibility Bioengineering Biology Bone morphogenetic proteins Bone Morphogenetic Proteins - metabolism Bone Morphogenetic Proteins - pharmacology Cell Line Cloning Colorectal cancer Cooperation Fractures Gene expression Genes, Reporter Genetic screening Genetic testing Genomes Growth factors Homeostasis Humans Influenza Journalists Kinases Laboratories Luciferase Mice Mice, Knockout Motility Mutation Osteoblasts - metabolism Proteins Screening Signal Transduction Signaling Tamoxifen
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