Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults
Berries and associated bioactive compounds, e.g. polyphenols and dietary fibre (DF), may have beneficial implications with respect to the metabolic syndrome, including also cognitive functions. The aim of this study was to evaluate effects on cognitive functions and cardiometabolic risk markers of 5...
Gespeichert in:
| Veröffentlicht in: | PloS one 2017-11, Vol.12 (11), p.e0188173-e0188173 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0188173 |
|---|---|
| container_issue | 11 |
| container_start_page | e0188173 |
| container_title | PloS one |
| container_volume | 12 |
| creator | Nilsson, Anne Salo, Ilkka Plaza, Merichel Björck, Inger |
| description | Berries and associated bioactive compounds, e.g. polyphenols and dietary fibre (DF), may have beneficial implications with respect to the metabolic syndrome, including also cognitive functions. The aim of this study was to evaluate effects on cognitive functions and cardiometabolic risk markers of 5 wk intervention with a mixture of berries, in healthy humans.
Forty healthy subjects between 50-70 years old were provided a berry beverage based on a mixture of berries (150g blueberries, 50g blackcurrant, 50g elderberry, 50g lingonberries, 50g strawberry, and 100g tomatoes) or a control beverage, daily during 5 weeks in a randomized crossover design. The control beverage (water based) was matched with respect to monosaccharides, pH, and volume. Cognitive tests included tests of working memory capacity, selective attention, and psychomotor reaction time. Cardiometabolic test variables investigated were blood pressure, fasting blood concentrations of glucose, insulin, blood lipids, inflammatory markers, and markers of oxidative stress.
The daily amounts of total polyphenols and DF from the berry beverage were 795 mg and 11g, respectively. There were no polyphenols or DF in the control beverage. The berry intervention reduced total- and LDL cholesterol compared to baseline (both P |
| doi_str_mv | 10.1371/journal.pone.0188173 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1964555485</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A514570577</galeid><doaj_id>oai_doaj_org_article_95e773b1170e4402b8832673cf6e8c09</doaj_id><sourcerecordid>A514570577</sourcerecordid><originalsourceid>FETCH-LOGICAL-c761t-3e33e37d195cbf2fd21e3335e2738b9edbf27a66262eceab6ff57606ac4107f93</originalsourceid><addsrcrecordid>eNqNk21r1TAUx4sobk6_gWhAEH1xr3lokhZBGGPqYDDw6W1I05O7bG1zTdK566fwI5v7sLHKXkibtpz8zj_NP-cUxXOC54RJ8u7Cj2HQ3XzpB5hjUlVEsgfFPqkZnQmK2cM733vFkxgvMOasEuJxsUdrUhJckv3iz7G1YFJE3iKNencNLWoghFV-XkHQC0B-QMYvBpfcFSA7DiY5P0SkhxYZHVrne0i68Z0zKLh4iXodLiHE9-gQhQz53v3Ooib4GGc-a6KYxnaF3IDOQXfpfIV81-awbscuxafFI6u7CM9274Pi-8fjb0efZ6dnn06ODk9nRgqSZgxYvmVLam4aS21LSY4wDlSyqqmhzUGphaCCggHdCGu5FFhokzcubc0Oipdb3WXno9qZGRWpRck5LyueiZMt0Xp9oZbB5Y2tlNdObQI-LJQOyZkOVM1BStYQIjGUJaZNVTEqJDNWQGXwerXTrVb8Bcuxmah14zKPJg8VQWlrKiNAq5oQrEqruWoaYKrC3FpiKWeMZrkPu58fmx5aA0MKupuoTmcGd64W_kpxUUlJRRZ4sxMI_ucIManeRQNdpwfw48YGTnlei2X01T_o_WbtqIXOfrjB-ryuWYuqQ05KLjHPDh0U83uofLXQO5ML2bocnyS8nSRkJsF1WugxRnXy9cv_s2c_puzrO-y2DqPvxk1pT8FyC27qN4C9NTmfzroPb9xQ6z5Uuz7MaS_uHtBt0k3jsb_1OC9C</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1964555485</pqid></control><display><type>article</type><title>Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>SWEPUB Freely available online</source><source>Public Library of Science (PLoS)</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Nilsson, Anne ; Salo, Ilkka ; Plaza, Merichel ; Björck, Inger</creator><contributor>Norata, Giuseppe Danilo</contributor><creatorcontrib>Nilsson, Anne ; Salo, Ilkka ; Plaza, Merichel ; Björck, Inger ; Norata, Giuseppe Danilo</creatorcontrib><description><![CDATA[Berries and associated bioactive compounds, e.g. polyphenols and dietary fibre (DF), may have beneficial implications with respect to the metabolic syndrome, including also cognitive functions. The aim of this study was to evaluate effects on cognitive functions and cardiometabolic risk markers of 5 wk intervention with a mixture of berries, in healthy humans.
Forty healthy subjects between 50-70 years old were provided a berry beverage based on a mixture of berries (150g blueberries, 50g blackcurrant, 50g elderberry, 50g lingonberries, 50g strawberry, and 100g tomatoes) or a control beverage, daily during 5 weeks in a randomized crossover design. The control beverage (water based) was matched with respect to monosaccharides, pH, and volume. Cognitive tests included tests of working memory capacity, selective attention, and psychomotor reaction time. Cardiometabolic test variables investigated were blood pressure, fasting blood concentrations of glucose, insulin, blood lipids, inflammatory markers, and markers of oxidative stress.
The daily amounts of total polyphenols and DF from the berry beverage were 795 mg and 11g, respectively. There were no polyphenols or DF in the control beverage. The berry intervention reduced total- and LDL cholesterol compared to baseline (both P<0.05), and in comparison to the control beverage (P<0.005 and P<0.01, respectively). The control beverage increased glucose concentrations (P<0.01) and tended to increase insulin concentrations (P = 0.064) from base line, and increased insulin concentrations in comparison to the berry beverage (P<0.05). Subjects performed better in the working memory test after the berry beverage compared to after the control beverage (P<0.05). No significant effects on the other test variables were observed.
The improvements in cardiometabolic risk markers and cognitive performance after the berry beverage suggest preventive potential of berries with respect to type 2 diabetes, cardiovascular disease, and associated cognitive decline. Possibly the polyphenols and DF contributed to the beneficial effects.
ClinicalTrials.gov: NCT01562392.]]></description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0188173</identifier><identifier>PMID: 29141041</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adults ; Berries ; Bioactive compounds ; Biology and Life Sciences ; Blood ; Blood pressure ; Blueberries ; Cardiovascular diseases ; Chemistry ; Cholesterol ; Cognition disorders ; Cognitive ability ; Cytokines ; Diabetes mellitus ; Diet ; Diet therapy ; Dietary fiber ; Ethics ; Food ; Fruits ; Glucose ; Health aspects ; Health risks ; Health Sciences ; Human subjects ; Hälsovetenskap ; Inflammation ; Insulin ; Insulin resistance ; Intervention ; Lipids ; Lipoproteins (low density) ; Low density lipoprotein ; Medical and Health Sciences ; Medicin och hälsovetenskap ; Medicine and Health Sciences ; Memory ; Metabolic disorders ; Metabolic syndrome ; Metabolites ; Monosaccharides ; Nutrition and Dietetics ; Nutrition research ; Nutritional aspects ; Näringslära ; Older people ; Oxidative stress ; pH effects ; Physical Sciences ; Phytochemicals ; Polyphenols ; Prevention ; Psychomotor performance ; Randomization ; Reaction time ; Short term memory ; Tomatoes</subject><ispartof>PloS one, 2017-11, Vol.12 (11), p.e0188173-e0188173</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Nilsson et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2017 Nilsson et al 2017 Nilsson et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c761t-3e33e37d195cbf2fd21e3335e2738b9edbf27a66262eceab6ff57606ac4107f93</citedby><cites>FETCH-LOGICAL-c761t-3e33e37d195cbf2fd21e3335e2738b9edbf27a66262eceab6ff57606ac4107f93</cites><orcidid>0000-0002-9780-7876</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687726/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687726/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,552,727,780,784,864,885,2100,2926,23865,27923,27924,53790,53792,79371,79372</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29141041$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://lup.lub.lu.se/record/afc8c6ea-9110-4fa5-bbe3-805ff1f25332$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><contributor>Norata, Giuseppe Danilo</contributor><creatorcontrib>Nilsson, Anne</creatorcontrib><creatorcontrib>Salo, Ilkka</creatorcontrib><creatorcontrib>Plaza, Merichel</creatorcontrib><creatorcontrib>Björck, Inger</creatorcontrib><title>Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults</title><title>PloS one</title><addtitle>PLoS One</addtitle><description><![CDATA[Berries and associated bioactive compounds, e.g. polyphenols and dietary fibre (DF), may have beneficial implications with respect to the metabolic syndrome, including also cognitive functions. The aim of this study was to evaluate effects on cognitive functions and cardiometabolic risk markers of 5 wk intervention with a mixture of berries, in healthy humans.
Forty healthy subjects between 50-70 years old were provided a berry beverage based on a mixture of berries (150g blueberries, 50g blackcurrant, 50g elderberry, 50g lingonberries, 50g strawberry, and 100g tomatoes) or a control beverage, daily during 5 weeks in a randomized crossover design. The control beverage (water based) was matched with respect to monosaccharides, pH, and volume. Cognitive tests included tests of working memory capacity, selective attention, and psychomotor reaction time. Cardiometabolic test variables investigated were blood pressure, fasting blood concentrations of glucose, insulin, blood lipids, inflammatory markers, and markers of oxidative stress.
The daily amounts of total polyphenols and DF from the berry beverage were 795 mg and 11g, respectively. There were no polyphenols or DF in the control beverage. The berry intervention reduced total- and LDL cholesterol compared to baseline (both P<0.05), and in comparison to the control beverage (P<0.005 and P<0.01, respectively). The control beverage increased glucose concentrations (P<0.01) and tended to increase insulin concentrations (P = 0.064) from base line, and increased insulin concentrations in comparison to the berry beverage (P<0.05). Subjects performed better in the working memory test after the berry beverage compared to after the control beverage (P<0.05). No significant effects on the other test variables were observed.
The improvements in cardiometabolic risk markers and cognitive performance after the berry beverage suggest preventive potential of berries with respect to type 2 diabetes, cardiovascular disease, and associated cognitive decline. Possibly the polyphenols and DF contributed to the beneficial effects.
ClinicalTrials.gov: NCT01562392.]]></description><subject>Adults</subject><subject>Berries</subject><subject>Bioactive compounds</subject><subject>Biology and Life Sciences</subject><subject>Blood</subject><subject>Blood pressure</subject><subject>Blueberries</subject><subject>Cardiovascular diseases</subject><subject>Chemistry</subject><subject>Cholesterol</subject><subject>Cognition disorders</subject><subject>Cognitive ability</subject><subject>Cytokines</subject><subject>Diabetes mellitus</subject><subject>Diet</subject><subject>Diet therapy</subject><subject>Dietary fiber</subject><subject>Ethics</subject><subject>Food</subject><subject>Fruits</subject><subject>Glucose</subject><subject>Health aspects</subject><subject>Health risks</subject><subject>Health Sciences</subject><subject>Human subjects</subject><subject>Hälsovetenskap</subject><subject>Inflammation</subject><subject>Insulin</subject><subject>Insulin resistance</subject><subject>Intervention</subject><subject>Lipids</subject><subject>Lipoproteins (low density)</subject><subject>Low density lipoprotein</subject><subject>Medical and Health Sciences</subject><subject>Medicin och hälsovetenskap</subject><subject>Medicine and Health Sciences</subject><subject>Memory</subject><subject>Metabolic disorders</subject><subject>Metabolic syndrome</subject><subject>Metabolites</subject><subject>Monosaccharides</subject><subject>Nutrition and Dietetics</subject><subject>Nutrition research</subject><subject>Nutritional aspects</subject><subject>Näringslära</subject><subject>Older people</subject><subject>Oxidative stress</subject><subject>pH effects</subject><subject>Physical Sciences</subject><subject>Phytochemicals</subject><subject>Polyphenols</subject><subject>Prevention</subject><subject>Psychomotor performance</subject><subject>Randomization</subject><subject>Reaction time</subject><subject>Short term memory</subject><subject>Tomatoes</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>D8T</sourceid><sourceid>DOA</sourceid><recordid>eNqNk21r1TAUx4sobk6_gWhAEH1xr3lokhZBGGPqYDDw6W1I05O7bG1zTdK566fwI5v7sLHKXkibtpz8zj_NP-cUxXOC54RJ8u7Cj2HQ3XzpB5hjUlVEsgfFPqkZnQmK2cM733vFkxgvMOasEuJxsUdrUhJckv3iz7G1YFJE3iKNencNLWoghFV-XkHQC0B-QMYvBpfcFSA7DiY5P0SkhxYZHVrne0i68Z0zKLh4iXodLiHE9-gQhQz53v3Ooib4GGc-a6KYxnaF3IDOQXfpfIV81-awbscuxafFI6u7CM9274Pi-8fjb0efZ6dnn06ODk9nRgqSZgxYvmVLam4aS21LSY4wDlSyqqmhzUGphaCCggHdCGu5FFhokzcubc0Oipdb3WXno9qZGRWpRck5LyueiZMt0Xp9oZbB5Y2tlNdObQI-LJQOyZkOVM1BStYQIjGUJaZNVTEqJDNWQGXwerXTrVb8Bcuxmah14zKPJg8VQWlrKiNAq5oQrEqruWoaYKrC3FpiKWeMZrkPu58fmx5aA0MKupuoTmcGd64W_kpxUUlJRRZ4sxMI_ucIManeRQNdpwfw48YGTnlei2X01T_o_WbtqIXOfrjB-ryuWYuqQ05KLjHPDh0U83uofLXQO5ML2bocnyS8nSRkJsF1WugxRnXy9cv_s2c_puzrO-y2DqPvxk1pT8FyC27qN4C9NTmfzroPb9xQ6z5Uuz7MaS_uHtBt0k3jsb_1OC9C</recordid><startdate>20171115</startdate><enddate>20171115</enddate><creator>Nilsson, Anne</creator><creator>Salo, Ilkka</creator><creator>Plaza, Merichel</creator><creator>Björck, Inger</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>ADTPV</scope><scope>AGCHP</scope><scope>AOWAS</scope><scope>D8T</scope><scope>D95</scope><scope>ZZAVC</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-9780-7876</orcidid></search><sort><creationdate>20171115</creationdate><title>Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults</title><author>Nilsson, Anne ; Salo, Ilkka ; Plaza, Merichel ; Björck, Inger</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c761t-3e33e37d195cbf2fd21e3335e2738b9edbf27a66262eceab6ff57606ac4107f93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adults</topic><topic>Berries</topic><topic>Bioactive compounds</topic><topic>Biology and Life Sciences</topic><topic>Blood</topic><topic>Blood pressure</topic><topic>Blueberries</topic><topic>Cardiovascular diseases</topic><topic>Chemistry</topic><topic>Cholesterol</topic><topic>Cognition disorders</topic><topic>Cognitive ability</topic><topic>Cytokines</topic><topic>Diabetes mellitus</topic><topic>Diet</topic><topic>Diet therapy</topic><topic>Dietary fiber</topic><topic>Ethics</topic><topic>Food</topic><topic>Fruits</topic><topic>Glucose</topic><topic>Health aspects</topic><topic>Health risks</topic><topic>Health Sciences</topic><topic>Human subjects</topic><topic>Hälsovetenskap</topic><topic>Inflammation</topic><topic>Insulin</topic><topic>Insulin resistance</topic><topic>Intervention</topic><topic>Lipids</topic><topic>Lipoproteins (low density)</topic><topic>Low density lipoprotein</topic><topic>Medical and Health Sciences</topic><topic>Medicin och hälsovetenskap</topic><topic>Medicine and Health Sciences</topic><topic>Memory</topic><topic>Metabolic disorders</topic><topic>Metabolic syndrome</topic><topic>Metabolites</topic><topic>Monosaccharides</topic><topic>Nutrition and Dietetics</topic><topic>Nutrition research</topic><topic>Nutritional aspects</topic><topic>Näringslära</topic><topic>Older people</topic><topic>Oxidative stress</topic><topic>pH effects</topic><topic>Physical Sciences</topic><topic>Phytochemicals</topic><topic>Polyphenols</topic><topic>Prevention</topic><topic>Psychomotor performance</topic><topic>Randomization</topic><topic>Reaction time</topic><topic>Short term memory</topic><topic>Tomatoes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nilsson, Anne</creatorcontrib><creatorcontrib>Salo, Ilkka</creatorcontrib><creatorcontrib>Plaza, Merichel</creatorcontrib><creatorcontrib>Björck, Inger</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>SwePub</collection><collection>SWEPUB Lunds universitet full text</collection><collection>SwePub Articles</collection><collection>SWEPUB Freely available online</collection><collection>SWEPUB Lunds universitet</collection><collection>SwePub Articles full text</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nilsson, Anne</au><au>Salo, Ilkka</au><au>Plaza, Merichel</au><au>Björck, Inger</au><au>Norata, Giuseppe Danilo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2017-11-15</date><risdate>2017</risdate><volume>12</volume><issue>11</issue><spage>e0188173</spage><epage>e0188173</epage><pages>e0188173-e0188173</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract><![CDATA[Berries and associated bioactive compounds, e.g. polyphenols and dietary fibre (DF), may have beneficial implications with respect to the metabolic syndrome, including also cognitive functions. The aim of this study was to evaluate effects on cognitive functions and cardiometabolic risk markers of 5 wk intervention with a mixture of berries, in healthy humans.
Forty healthy subjects between 50-70 years old were provided a berry beverage based on a mixture of berries (150g blueberries, 50g blackcurrant, 50g elderberry, 50g lingonberries, 50g strawberry, and 100g tomatoes) or a control beverage, daily during 5 weeks in a randomized crossover design. The control beverage (water based) was matched with respect to monosaccharides, pH, and volume. Cognitive tests included tests of working memory capacity, selective attention, and psychomotor reaction time. Cardiometabolic test variables investigated were blood pressure, fasting blood concentrations of glucose, insulin, blood lipids, inflammatory markers, and markers of oxidative stress.
The daily amounts of total polyphenols and DF from the berry beverage were 795 mg and 11g, respectively. There were no polyphenols or DF in the control beverage. The berry intervention reduced total- and LDL cholesterol compared to baseline (both P<0.05), and in comparison to the control beverage (P<0.005 and P<0.01, respectively). The control beverage increased glucose concentrations (P<0.01) and tended to increase insulin concentrations (P = 0.064) from base line, and increased insulin concentrations in comparison to the berry beverage (P<0.05). Subjects performed better in the working memory test after the berry beverage compared to after the control beverage (P<0.05). No significant effects on the other test variables were observed.
The improvements in cardiometabolic risk markers and cognitive performance after the berry beverage suggest preventive potential of berries with respect to type 2 diabetes, cardiovascular disease, and associated cognitive decline. Possibly the polyphenols and DF contributed to the beneficial effects.
ClinicalTrials.gov: NCT01562392.]]></abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>29141041</pmid><doi>10.1371/journal.pone.0188173</doi><tpages>e0188173</tpages><orcidid>https://orcid.org/0000-0002-9780-7876</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2017-11, Vol.12 (11), p.e0188173-e0188173 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1964555485 |
| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; SWEPUB Freely available online; Public Library of Science (PLoS); PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Adults Berries Bioactive compounds Biology and Life Sciences Blood Blood pressure Blueberries Cardiovascular diseases Chemistry Cholesterol Cognition disorders Cognitive ability Cytokines Diabetes mellitus Diet Diet therapy Dietary fiber Ethics Food Fruits Glucose Health aspects Health risks Health Sciences Human subjects Hälsovetenskap Inflammation Insulin Insulin resistance Intervention Lipids Lipoproteins (low density) Low density lipoprotein Medical and Health Sciences Medicin och hälsovetenskap Medicine and Health Sciences Memory Metabolic disorders Metabolic syndrome Metabolites Monosaccharides Nutrition and Dietetics Nutrition research Nutritional aspects Näringslära Older people Oxidative stress pH effects Physical Sciences Phytochemicals Polyphenols Prevention Psychomotor performance Randomization Reaction time Short term memory Tomatoes |
| title | Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T19%3A47%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20a%20mixed%20berry%20beverage%20on%20cognitive%20functions%20and%20cardiometabolic%20risk%20markers;%20A%20randomized%20cross-over%20study%20in%20healthy%20older%20adults&rft.jtitle=PloS%20one&rft.au=Nilsson,%20Anne&rft.date=2017-11-15&rft.volume=12&rft.issue=11&rft.spage=e0188173&rft.epage=e0188173&rft.pages=e0188173-e0188173&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0188173&rft_dat=%3Cgale_plos_%3EA514570577%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1964555485&rft_id=info:pmid/29141041&rft_galeid=A514570577&rft_doaj_id=oai_doaj_org_article_95e773b1170e4402b8832673cf6e8c09&rfr_iscdi=true |