Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids

Clostridium botulinum and related clostridial species express extremely potent neurotoxins known as botulinum neurotoxins (BoNTs) that cause long-lasting, potentially fatal intoxications in humans and other mammals. The amino acid variation within the BoNT is used to categorize the species into seve...

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Veröffentlicht in:	PloS one 2007-12, Vol.2 (12), p.e1271
Hauptverfasser:	Smith, Theresa J, Hill, Karen K, Foley, Brian T, Detter, John C, Munk, A Christine, Bruce, David C, Doggett, Norman A, Smith, Leonard A, Marks, James D, Xie, Gary, Brettin, Thomas S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Analysis Bacteria Botulinum toxin Botulinum Toxins - genetics Botulism Cloning, Molecular Clostridium Clostridium botulinum Clostridium botulinum - genetics Clostridium tetani Clusters Food contamination Gastrointestinal diseases Gene duplication Gene sequencing Genes Genetic diversity Genetics and Genomics/Bioinformatics Genetics and Genomics/Genome Projects Genetics and Genomics/Microbial Evolution and Genomics Genomes Infectious diseases Insertion Metabolism Multigene Family Neurotoxins Phylogenetics Plasmids Proteins Recombination Serotypes Toxicology Toxins Waterborne diseases
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