HIV-1/HSV-2 co-infected adults in early HIV-1 infection have elevated CD4+ T cell counts

HIV-1 is often acquired in the presence of pre-existing co-infections, such as Herpes Simplex Virus 2 (HSV-2). We examined the impact of HSV-2 status at the time of HIV-1 acquisition for its impact on subsequent clinical course, and total CD4+ T cell phenotypes. We assessed the relationship of HSV-1...

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Veröffentlicht in:	PloS one 2007-10, Vol.2 (10), p.e1080-e1080
Hauptverfasser:	Barbour, Jason D, Sauer, Mariana M, Sharp, Elizabeth R, Garrison, Keith E, Long, Brian R, Tomiyama, Helena, Bassichetto, Katia C, Oliveira, Solange M, Abbate, Maria C, Nixon, Douglas F, Kallas, Esper G
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult Adults AIDS Antiretroviral drugs Bacterial infections CD4 antigen CD4 Lymphocyte Count CD4-Positive T-Lymphocytes - cytology CD4-Positive T-Lymphocytes - immunology CD8 antigen Cell activation Cell differentiation Differentiation Female Herpes simplex Herpes Simplex - blood Herpes Simplex - complications Herpes viruses Herpesvirus 2, Human - metabolism HIV HIV Infections - blood HIV Infections - complications HIV Infections - metabolism HIV-1 - metabolism Human immunodeficiency virus Humans Immune system Immunology Immunology/Immunity to Infections Immunology/Immunomodulation Infections Infectious Diseases Infectious Diseases/HIV Infection and AIDS Infectious Diseases/Sexually Transmitted Diseases Infectious Diseases/Viral Infections Inflammation Lymphocytes Lymphocytes T Male Medical research Medicine Mens health Models, Biological Phenotype Plasma Public health Public Health and Epidemiology/Infectious Diseases Ribonucleic acid RNA RNA, Viral - metabolism T cells Vaccines Viral Load Virology Virology/Diagnosis Virology/Persistence and Latency Viruses
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