Differential drug resistance acquisition in HIV-1 of subtypes B and C

Subtype C is the most prevalent HIV-1 subtype in the world, mainly in countries with the highest HIV prevalence. However, few studies have evaluated the impact of antiretroviral therapy on this subtype. In southern Brazil, the first developing country to offer free and universal treatment, subtypes...

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Veröffentlicht in:	PloS one 2007-08, Vol.2 (8), p.e730-e730
Hauptverfasser:	Soares, Esmeralda A J M, Santos, André F A, Sousa, Thatiana M, Sprinz, Eduardo, Martinez, Ana M B, Silveira, Jussara, Tanuri, Amilcar, Soares, Marcelo A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Anti-HIV Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiretroviral Therapy, Highly Active Brazil Developing countries Drug resistance Drug Resistance, Viral Exposure Female Gene sequencing Highly active antiretroviral therapy HIV HIV Infections - drug therapy HIV-1 - drug effects HIV-1 - genetics HIV-1 - metabolism Human immunodeficiency virus Humans Infectious Diseases/Antimicrobials and Drug Resistance Infectious Diseases/HIV Infection and AIDS Infectious Diseases/Viral Infections LDCs Male Middle Aged Mutation Patients Protease inhibitors Ribonucleic acid RNA RNA, Viral - genetics RNA, Viral - metabolism RNA-directed DNA polymerase Statistical analysis Therapy Viral Load Viremia Virology/Antivirals, including Modes of Action and Resistance Virology/Immunodeficiency Viruses
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