Surprisingly high specificity of the PPD skin test for M. tuberculosis infection from recent exposure in The Gambia

Options for intervention against Mycobacterium tuberculosis infection are limited by the diagnostic tools available. The Purified Protein Derivative (PPD) skin test is thought to be non-specific, especially in tropical settings. We compared the PPD skin test with an ELISPOT test in The Gambia. House...

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Veröffentlicht in:	PloS one 2006-12, Vol.1 (1), p.e68-e68
Hauptverfasser:	Hill, Philip C, Brookes, Roger H, Fox, Annette, Jackson-Sillah, Dolly, Lugos, Moses D, Jeffries, David J, Donkor, Simon A, Adegbola, Richard A, McAdam, Keith P W J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antigens Antigens, Bacterial - immunology Bacterial Proteins - immunology Case-Control Studies Child Child, Preschool Communities Contact Contact Tracing - methods Contact Tracing - statistics & numerical data Diagnosis Diagnostic software Diagnostic systems Enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - methods Enzyme-Linked Immunosorbent Assay - statistics & numerical data Epidemics ESAT-6 antigen Exposure Female Gambia - epidemiology Health aspects Households Housing Humans Immunology/Immune Response Infant Infections Infectious Diseases Infectious Diseases/Bacterial Infections Laboratories Lymphocytes T Male Medical diagnosis Medical tests Middle Aged Mycobacterium tuberculosis Prophylaxis Regression analysis Sensitivity and Specificity Skin Skin tests Smear Sputum T cells T-Lymphocytes - immunology Tuberculin Tuberculin Test - statistics & numerical data Tuberculosis Tuberculosis, Pulmonary - diagnosis Tuberculosis, Pulmonary - epidemiology Tuberculosis, Pulmonary - prevention & control Tuberculosis, Pulmonary - transmission Ultrasonic testing
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