Real-time PCR in detection and quantitation of Leishmania donovani for the diagnosis of Visceral Leishmaniasis patients and the monitoring of their response to treatment

Sustained elimination of Visceral Leishmaniasis (VL) requires the reduction and control of parasite reservoirs to minimize the transmission of Leishmania donovani infection. A simple, reproducible and definitive diagnostic procedure is therefore indispensable for the early and accurate detection of...

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Veröffentlicht in:	PloS one 2017-09, Vol.12 (9), p.e0185606-e0185606
Hauptverfasser:	Hossain, Faria, Ghosh, Prakash, Khan, Md Anik Ashfaq, Duthie, Malcolm S, Vallur, Aarthy C, Picone, Alessandro, Howard, Randall F, Reed, Steven G, Mondal, Dinesh
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Assaying Biology and Life Sciences Blood Bone marrow Buffy coat Care and treatment Case-Control Studies Child Deoxyribonucleic acid Diagnosis Diagnostic systems Discordance Disease transmission DNA DNA, Protozoan - metabolism Female Fever Genetic aspects Genomes Health aspects Humans Infections Infectious diseases Laboratories Leishmania donovani - genetics Leishmaniasis, Visceral - diagnosis Leishmaniasis, Visceral - drug therapy Male Medical diagnosis Medicine and Health Sciences Microscopy Monitoring, Physiologic - methods Nutrition Parasite control Parasites Parasitic diseases Parasitology Patients Peripheral blood Polymerase chain reaction Quantitation Real time Real-Time Polymerase Chain Reaction - methods Reproducibility of Results Research and Analysis Methods Reservoirs Sensitivity Sensitivity and Specificity Skin Studies Tuberculosis Vector-borne diseases Visceral leishmaniasis Young Adult
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