Vascular calcification and cardiac function according to residual renal function in patients on hemodialysis with urination
Vascular calcification is common and may affect cardiac function in patients with end-stage renal disease (ESRD). However, little is known about the effect of residual renal function on vascular calcification and cardiac function in patients on hemodialysis. This study was conducted between January...
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| Veröffentlicht in: | PloS one 2017-09, Vol.12 (9), p.e0185296-e0185296 |
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| creator | Shin, Dong Ho Lee, Young-Ki Oh, Jieun Yoon, Jong-Woo Rhee, So Yon Kim, Eun-Jung Ryu, Jiwon Cho, Ajin Jeon, Hee Jung Choi, Myung-Jin Noh, Jung-Woo |
| description | Vascular calcification is common and may affect cardiac function in patients with end-stage renal disease (ESRD). However, little is known about the effect of residual renal function on vascular calcification and cardiac function in patients on hemodialysis.
This study was conducted between January 2014 and January 2017. One hundred six patients with residual renal function on maintenance hemodialysis for 3 months were recruited. We used residual renal urea clearance (KRU) to measure residual renal function. First, abdominal aortic calcification score (AACS) and brachial-ankle pulse wave velocity (baPWV) were measured in patients on hemodialysis. Second, we performed echocardiography and investigated new cardiovascular events after study enrollment.
The median KRU was 0.9 (0.3-2.5) mL/min/1.73m2. AACS (4.0 [1.0-10.0] vs. 3.0 [0.0-8.0], p = 0.05) and baPWV (1836.1 ± 250.4 vs. 1676.8 ± 311.0 cm/s, p = 0.01) were significantly higher in patients with a KRU < 0.9 mL/min/1.73m2 than a KRU ≥ 0.9 mL/min/1.73m2. Log-KRU significantly negatively correlated with log-AACS (ß = -0.29, p = 0.002) and baPWV (ß = -0.19, P = 0.05) after factor adjustment. The proportion of left ventricular diastolic dysfunction was significantly higher in patients with a KRU < 0.9 mL/min/1.73m2 than with a KRU ≥ 0.9 mL/min/1.73m2 (67.9% vs. 49.1%, p = 0.05). Patients with a KRU < 0.9 mL/min/1.73m2 showed a higher tendency of cumulative cardiovascular events compared to those with a KRU ≥ 0.9 ml/min/1.73m2 (P = 0.08).
Residual renal function was significantly associated with vascular calcification and left ventricular diastolic dysfunction in patients on hemodialysis. |
| doi_str_mv | 10.1371/journal.pone.0185296 |
| format | Article |
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This study was conducted between January 2014 and January 2017. One hundred six patients with residual renal function on maintenance hemodialysis for 3 months were recruited. We used residual renal urea clearance (KRU) to measure residual renal function. First, abdominal aortic calcification score (AACS) and brachial-ankle pulse wave velocity (baPWV) were measured in patients on hemodialysis. Second, we performed echocardiography and investigated new cardiovascular events after study enrollment.
The median KRU was 0.9 (0.3-2.5) mL/min/1.73m2. AACS (4.0 [1.0-10.0] vs. 3.0 [0.0-8.0], p = 0.05) and baPWV (1836.1 ± 250.4 vs. 1676.8 ± 311.0 cm/s, p = 0.01) were significantly higher in patients with a KRU < 0.9 mL/min/1.73m2 than a KRU ≥ 0.9 mL/min/1.73m2. Log-KRU significantly negatively correlated with log-AACS (ß = -0.29, p = 0.002) and baPWV (ß = -0.19, P = 0.05) after factor adjustment. The proportion of left ventricular diastolic dysfunction was significantly higher in patients with a KRU < 0.9 mL/min/1.73m2 than with a KRU ≥ 0.9 mL/min/1.73m2 (67.9% vs. 49.1%, p = 0.05). Patients with a KRU < 0.9 mL/min/1.73m2 showed a higher tendency of cumulative cardiovascular events compared to those with a KRU ≥ 0.9 ml/min/1.73m2 (P = 0.08).
Residual renal function was significantly associated with vascular calcification and left ventricular diastolic dysfunction in patients on hemodialysis.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0185296</identifier><identifier>PMID: 28953969</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Anemia ; Ankle ; Ankle Brachial Index ; Aorta ; Aorta, Abdominal - pathology ; Aorta, Abdominal - physiopathology ; Biology and Life Sciences ; Calcification ; Calcification (ectopic) ; Calcification (Physiology) ; Cardiovascular disease ; Care and treatment ; Chronic kidney failure ; Complications and side effects ; Demography ; Dialysis ; Echocardiography ; End-stage renal disease ; Female ; Heart diseases ; Heart failure ; Heart Function Tests ; Hemodialysis ; Humans ; Inflammation ; Internal medicine ; Kaplan-Meier Estimate ; Kidney - physiopathology ; Kidney diseases ; Kidney Function Tests ; Kidney transplantation ; Male ; Medicine ; Medicine and Health Sciences ; Middle Aged ; Mortality ; Patient outcomes ; Patients ; Peritoneal dialysis ; Physical Sciences ; Physicians ; Pulse Wave Analysis ; Renal Dialysis ; Renal function ; Risk factors ; Studies ; Transplants & implants ; Urea ; Urea - metabolism ; Urination ; Urination - physiology ; Vascular Calcification - diagnostic imaging ; Vascular Calcification - physiopathology ; Ventricle ; Wave velocity</subject><ispartof>PloS one, 2017-09, Vol.12 (9), p.e0185296-e0185296</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Shin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2017 Shin et al 2017 Shin et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c585t-8f092306e34eca93f0dd41225015b771f22a68fd0ecabb96f40304c7f23321c3</citedby><cites>FETCH-LOGICAL-c585t-8f092306e34eca93f0dd41225015b771f22a68fd0ecabb96f40304c7f23321c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617191/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617191/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79569,79570</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28953969$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shin, Dong Ho</creatorcontrib><creatorcontrib>Lee, Young-Ki</creatorcontrib><creatorcontrib>Oh, Jieun</creatorcontrib><creatorcontrib>Yoon, Jong-Woo</creatorcontrib><creatorcontrib>Rhee, So Yon</creatorcontrib><creatorcontrib>Kim, Eun-Jung</creatorcontrib><creatorcontrib>Ryu, Jiwon</creatorcontrib><creatorcontrib>Cho, Ajin</creatorcontrib><creatorcontrib>Jeon, Hee Jung</creatorcontrib><creatorcontrib>Choi, Myung-Jin</creatorcontrib><creatorcontrib>Noh, Jung-Woo</creatorcontrib><title>Vascular calcification and cardiac function according to residual renal function in patients on hemodialysis with urination</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Vascular calcification is common and may affect cardiac function in patients with end-stage renal disease (ESRD). However, little is known about the effect of residual renal function on vascular calcification and cardiac function in patients on hemodialysis.
This study was conducted between January 2014 and January 2017. One hundred six patients with residual renal function on maintenance hemodialysis for 3 months were recruited. We used residual renal urea clearance (KRU) to measure residual renal function. First, abdominal aortic calcification score (AACS) and brachial-ankle pulse wave velocity (baPWV) were measured in patients on hemodialysis. Second, we performed echocardiography and investigated new cardiovascular events after study enrollment.
The median KRU was 0.9 (0.3-2.5) mL/min/1.73m2. AACS (4.0 [1.0-10.0] vs. 3.0 [0.0-8.0], p = 0.05) and baPWV (1836.1 ± 250.4 vs. 1676.8 ± 311.0 cm/s, p = 0.01) were significantly higher in patients with a KRU < 0.9 mL/min/1.73m2 than a KRU ≥ 0.9 mL/min/1.73m2. Log-KRU significantly negatively correlated with log-AACS (ß = -0.29, p = 0.002) and baPWV (ß = -0.19, P = 0.05) after factor adjustment. The proportion of left ventricular diastolic dysfunction was significantly higher in patients with a KRU < 0.9 mL/min/1.73m2 than with a KRU ≥ 0.9 mL/min/1.73m2 (67.9% vs. 49.1%, p = 0.05). Patients with a KRU < 0.9 mL/min/1.73m2 showed a higher tendency of cumulative cardiovascular events compared to those with a KRU ≥ 0.9 ml/min/1.73m2 (P = 0.08).
Residual renal function was significantly associated with vascular calcification and left ventricular diastolic dysfunction in patients on hemodialysis.</description><subject>Anemia</subject><subject>Ankle</subject><subject>Ankle Brachial Index</subject><subject>Aorta</subject><subject>Aorta, Abdominal - pathology</subject><subject>Aorta, Abdominal - physiopathology</subject><subject>Biology and Life Sciences</subject><subject>Calcification</subject><subject>Calcification (ectopic)</subject><subject>Calcification (Physiology)</subject><subject>Cardiovascular disease</subject><subject>Care and treatment</subject><subject>Chronic kidney failure</subject><subject>Complications and side effects</subject><subject>Demography</subject><subject>Dialysis</subject><subject>Echocardiography</subject><subject>End-stage renal disease</subject><subject>Female</subject><subject>Heart diseases</subject><subject>Heart failure</subject><subject>Heart Function Tests</subject><subject>Hemodialysis</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Internal medicine</subject><subject>Kaplan-Meier Estimate</subject><subject>Kidney - physiopathology</subject><subject>Kidney diseases</subject><subject>Kidney Function Tests</subject><subject>Kidney transplantation</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Peritoneal dialysis</subject><subject>Physical Sciences</subject><subject>Physicians</subject><subject>Pulse Wave Analysis</subject><subject>Renal Dialysis</subject><subject>Renal function</subject><subject>Risk factors</subject><subject>Studies</subject><subject>Transplants & implants</subject><subject>Urea</subject><subject>Urea - metabolism</subject><subject>Urination</subject><subject>Urination - physiology</subject><subject>Vascular Calcification - diagnostic imaging</subject><subject>Vascular Calcification - physiopathology</subject><subject>Ventricle</subject><subject>Wave velocity</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNptkk1vEzEQhlcIREvgHyBYCQlxSRjba3t9QaqqApUqcam4Wl6vnThy7GDvFlX8-TrJtiSIk8czj9_58FTVWwQLRDj6vI5jCsovtjGYBaCWYsGeVedIEDxnGMjzI_usepXzGoCSlrGX1RluBSWCifPqz0-V9ehVqrXy2lmn1eBiqFXoiyf1TunajkEfnFrH4grLeoh1Mtn1o_LFKGX8hVyot0XDhCHX5boym1hU_H12uf7thlU9Jhf2SV5XL6zy2byZzll1-_Xq9vL7_ObHt-vLi5u5pi0d5q0FgQkwQxqjlSAW-r5BGFNAtOMcWYwVa20PJdp1gtkGCDSaW0wIRprMqvcH2a2PWU5jyxKJhjDUEmgLcX0g-qjWcpvcRqV7GZWTe0dMS6nS4LQ3ElDPqUFGA-aNwtA1tOdAW4056A6hovVlyjZ2G9PrMoek_InoaSS4lVzGO0kZ4kjsBD5NAin-Gk0e5MZlbbxXwcRxX3fTEIFLd7Pqwz_o_7ubqKUqDbhgY8mrd6LyggJrOWfACvXxiFoZ5YdVjn7cfVQ-BZsDqFPMORn71BsCudvMxyLkbjPltJnl2bvjuTw9elxF8gDl1-HJ</recordid><startdate>20170927</startdate><enddate>20170927</enddate><creator>Shin, Dong Ho</creator><creator>Lee, Young-Ki</creator><creator>Oh, Jieun</creator><creator>Yoon, Jong-Woo</creator><creator>Rhee, So Yon</creator><creator>Kim, Eun-Jung</creator><creator>Ryu, Jiwon</creator><creator>Cho, Ajin</creator><creator>Jeon, Hee Jung</creator><creator>Choi, Myung-Jin</creator><creator>Noh, Jung-Woo</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20170927</creationdate><title>Vascular calcification and cardiac function according to residual renal function in patients on hemodialysis with urination</title><author>Shin, Dong Ho ; Lee, Young-Ki ; Oh, Jieun ; Yoon, Jong-Woo ; Rhee, So Yon ; Kim, Eun-Jung ; Ryu, Jiwon ; Cho, Ajin ; Jeon, Hee Jung ; Choi, Myung-Jin ; Noh, Jung-Woo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c585t-8f092306e34eca93f0dd41225015b771f22a68fd0ecabb96f40304c7f23321c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Anemia</topic><topic>Ankle</topic><topic>Ankle Brachial Index</topic><topic>Aorta</topic><topic>Aorta, Abdominal - pathology</topic><topic>Aorta, Abdominal - physiopathology</topic><topic>Biology and Life Sciences</topic><topic>Calcification</topic><topic>Calcification (ectopic)</topic><topic>Calcification (Physiology)</topic><topic>Cardiovascular disease</topic><topic>Care and treatment</topic><topic>Chronic kidney failure</topic><topic>Complications and side effects</topic><topic>Demography</topic><topic>Dialysis</topic><topic>Echocardiography</topic><topic>End-stage renal disease</topic><topic>Female</topic><topic>Heart diseases</topic><topic>Heart failure</topic><topic>Heart Function Tests</topic><topic>Hemodialysis</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Internal medicine</topic><topic>Kaplan-Meier Estimate</topic><topic>Kidney - physiopathology</topic><topic>Kidney diseases</topic><topic>Kidney Function Tests</topic><topic>Kidney transplantation</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>Peritoneal dialysis</topic><topic>Physical Sciences</topic><topic>Physicians</topic><topic>Pulse Wave Analysis</topic><topic>Renal Dialysis</topic><topic>Renal function</topic><topic>Risk factors</topic><topic>Studies</topic><topic>Transplants & implants</topic><topic>Urea</topic><topic>Urea - metabolism</topic><topic>Urination</topic><topic>Urination - physiology</topic><topic>Vascular Calcification - diagnostic imaging</topic><topic>Vascular Calcification - physiopathology</topic><topic>Ventricle</topic><topic>Wave velocity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shin, Dong Ho</creatorcontrib><creatorcontrib>Lee, Young-Ki</creatorcontrib><creatorcontrib>Oh, Jieun</creatorcontrib><creatorcontrib>Yoon, Jong-Woo</creatorcontrib><creatorcontrib>Rhee, So Yon</creatorcontrib><creatorcontrib>Kim, Eun-Jung</creatorcontrib><creatorcontrib>Ryu, Jiwon</creatorcontrib><creatorcontrib>Cho, Ajin</creatorcontrib><creatorcontrib>Jeon, Hee Jung</creatorcontrib><creatorcontrib>Choi, Myung-Jin</creatorcontrib><creatorcontrib>Noh, Jung-Woo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection (ProQuest)</collection><collection>Natural Science Collection (ProQuest)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shin, Dong Ho</au><au>Lee, Young-Ki</au><au>Oh, Jieun</au><au>Yoon, Jong-Woo</au><au>Rhee, So Yon</au><au>Kim, Eun-Jung</au><au>Ryu, Jiwon</au><au>Cho, Ajin</au><au>Jeon, Hee Jung</au><au>Choi, Myung-Jin</au><au>Noh, Jung-Woo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vascular calcification and cardiac function according to residual renal function in patients on hemodialysis with urination</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2017-09-27</date><risdate>2017</risdate><volume>12</volume><issue>9</issue><spage>e0185296</spage><epage>e0185296</epage><pages>e0185296-e0185296</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Vascular calcification is common and may affect cardiac function in patients with end-stage renal disease (ESRD). However, little is known about the effect of residual renal function on vascular calcification and cardiac function in patients on hemodialysis.
This study was conducted between January 2014 and January 2017. One hundred six patients with residual renal function on maintenance hemodialysis for 3 months were recruited. We used residual renal urea clearance (KRU) to measure residual renal function. First, abdominal aortic calcification score (AACS) and brachial-ankle pulse wave velocity (baPWV) were measured in patients on hemodialysis. Second, we performed echocardiography and investigated new cardiovascular events after study enrollment.
The median KRU was 0.9 (0.3-2.5) mL/min/1.73m2. AACS (4.0 [1.0-10.0] vs. 3.0 [0.0-8.0], p = 0.05) and baPWV (1836.1 ± 250.4 vs. 1676.8 ± 311.0 cm/s, p = 0.01) were significantly higher in patients with a KRU < 0.9 mL/min/1.73m2 than a KRU ≥ 0.9 mL/min/1.73m2. Log-KRU significantly negatively correlated with log-AACS (ß = -0.29, p = 0.002) and baPWV (ß = -0.19, P = 0.05) after factor adjustment. The proportion of left ventricular diastolic dysfunction was significantly higher in patients with a KRU < 0.9 mL/min/1.73m2 than with a KRU ≥ 0.9 mL/min/1.73m2 (67.9% vs. 49.1%, p = 0.05). Patients with a KRU < 0.9 mL/min/1.73m2 showed a higher tendency of cumulative cardiovascular events compared to those with a KRU ≥ 0.9 ml/min/1.73m2 (P = 0.08).
Residual renal function was significantly associated with vascular calcification and left ventricular diastolic dysfunction in patients on hemodialysis.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>28953969</pmid><doi>10.1371/journal.pone.0185296</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2017-09, Vol.12 (9), p.e0185296-e0185296 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1943618308 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Anemia Ankle Ankle Brachial Index Aorta Aorta, Abdominal - pathology Aorta, Abdominal - physiopathology Biology and Life Sciences Calcification Calcification (ectopic) Calcification (Physiology) Cardiovascular disease Care and treatment Chronic kidney failure Complications and side effects Demography Dialysis Echocardiography End-stage renal disease Female Heart diseases Heart failure Heart Function Tests Hemodialysis Humans Inflammation Internal medicine Kaplan-Meier Estimate Kidney - physiopathology Kidney diseases Kidney Function Tests Kidney transplantation Male Medicine Medicine and Health Sciences Middle Aged Mortality Patient outcomes Patients Peritoneal dialysis Physical Sciences Physicians Pulse Wave Analysis Renal Dialysis Renal function Risk factors Studies Transplants & implants Urea Urea - metabolism Urination Urination - physiology Vascular Calcification - diagnostic imaging Vascular Calcification - physiopathology Ventricle Wave velocity |
| title | Vascular calcification and cardiac function according to residual renal function in patients on hemodialysis with urination |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-18T22%3A59%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Vascular%20calcification%20and%20cardiac%20function%20according%20to%20residual%20renal%20function%20in%20patients%20on%20hemodialysis%20with%20urination&rft.jtitle=PloS%20one&rft.au=Shin,%20Dong%20Ho&rft.date=2017-09-27&rft.volume=12&rft.issue=9&rft.spage=e0185296&rft.epage=e0185296&rft.pages=e0185296-e0185296&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0185296&rft_dat=%3Cgale_plos_%3EA506877606%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1943618308&rft_id=info:pmid/28953969&rft_galeid=A506877606&rft_doaj_id=oai_doaj_org_article_01d75e1ec0274a20b45d7058c270cb11&rfr_iscdi=true |