Functional characterization of T-cells from palatine tonsils in patients with chronic tonsillitis

The palatine tonsils, localized in the oropharynx, are easily accessible secondary lymphoid tissue in humans. Inflammation of the palatine tonsils, local and chronic in case of chronic tonsillitis (CT) or acute in the presence of a peritonsillar abscess (PTA), ranks among the most common diseases in...

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Veröffentlicht in:	PloS one 2017-09, Vol.12 (9), p.e0183214-e0183214
Hauptverfasser:	Geißler, Katharina, Markwart, Robby, Requardt, Robert Pascal, Weigel, Cynthia, Schubert, Katja, Scherag, André, Rubio, Ignacio, Guntinas-Lichius, Orlando
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Airway management Antigens Bacteria Bacterial diseases Biology and Life Sciences Biomarkers - metabolism Blood CD4 antigen CD8-Positive T-Lymphocytes - immunology Cell Proliferation Chronic Disease Chronic infection Cytometry Diagnosis Disease control Exhaustion Female Flow cytometry Helper cells Hospitals Humans Immune response Immune system Immunology Immunophenotyping Immunosuppression Therapy Inflammation Kinases Lymphatic system Lymphocyte Activation - immunology Lymphocyte Count Lymphocytes Lymphocytes T Lymphoid tissue Male Medicine and Health Sciences Middle Aged Nosocomial infections Oropharynx Otolaryngology Palatine Tonsil - immunology Palatine Tonsil - pathology Patients PD-1 protein Peritonsillar Abscess - immunology Peritonsillar Abscess - pathology Phenotype Receptors, Immunologic - metabolism Research and Analysis Methods Risk factors Sepsis Signal Transduction - immunology Stimulation Studies T cell receptors T cells T-cell receptor T-Lymphocytes - immunology T-Lymphocytes, Regulatory - immunology Tendinosis Throat surgery Tonsillitis Tonsillitis - immunology Tonsillitis - pathology Viral infections Young Adult
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